Pharmapedia Pro
Medicines/Generics/Dimethyl Fumarate

Dimethyl Fumarate

Generic medicine reference

Not yet clinically reviewed

This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.

Spot an error in this entry? Submit a correction
Overview
Dimethyl fumarate is used for multiple sclerosis to help decrease the number of flare-ups (relapses), delay the progression of physical disability, and slow brain lesion development. Dimethyl fumarate (Brand: Tecfidera ) is FDA-approved in adults to treat relapsing forms of multiple sclerosis (MS), including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease. Dimethyl fumarate is a delayed-release capsule that is taken twice daily. Dimethyl fumarate is available under the brand name Tecfidera by Biogen Inc., and now also available as a generic.
Indications
Dimethyl fumarate is used for multiple sclerosis to help decrease the number of flare-ups (relapses), delay the progression of physical disability, and slow brain lesion development. Dimethyl fumarate (Brand: Tecfidera ) is FDA-approved in adults to treat relapsing forms of multiple sclerosis (MS), including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease. Dimethyl fumarate is a delayed-release capsule that is taken twice daily. Dimethyl fumarate is available under the brand name Tecfidera by Biogen Inc., and now also available as a generic.
Contraindications
You should not use diethyl fumarate if you have had a severe allergic reaction to dimethyl fumarate or diroximel fumarate ( Vumerity ). Tell your doctor if you have ever had: an active infection; or low white blood cell (WBC) counts. Tell your doctor if you are pregnant or breastfeeding. If you are pregnant, your name may be listed on a pregnancy registry to track the effects of dimethyl fumarate on the baby. Dimethyl fumarate is not approved for use by anyone younger than 18 years old.
Side Effects
The symptomatic adverse reactions produced by Dimethyl Fumarate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Diarrhea, Abdominal pain, Flushing.
Warnings
This medicine may cause a serious brain infection that can lead to disability or death. Call your doctor right away if you have problems with speech, thought, vision, or muscle movement. These symptoms may start gradually and get worse quickly.
High Risk Groups
This medicine may cause a serious brain infection that can lead to disability or death. Call your doctor right away if you have problems with speech, thought, vision, or muscle movement. These symptoms may start gradually and get worse quickly.
Adult Dosage
Scraped Dose — Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using dimethyl fumarate. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. You may take dimethyl fumarate with or without food. Taking the medicine with food may help prevent flushing (sudden warmth, redness, or tingly feeling). Swallow the capsule whole, and do not crush, chew, break, or open it. While using dimethyl fumarate, you will need frequent blood tests. Store this medicine in the original container at room temperature, away from moisture, heat, and light.
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Other drugs may affect dimethyl fumarate, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Storage
Delayed release Capsule Store Between 20°C-25°C. Protect from Sunlight.

Available Brands in Pakistan

No brands are recorded for this generic.