Medicines/Generics/Dipyrone

Dipyrone

Generic medicine reference

Not yet clinically reviewed

This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.

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Overview

Dipyrone is a pyrazolone analgesic and antipyretic drug, now seldom used because of its side effects. Dipyrone is NSAID (non-steroidal anti-inflammatory drug). Dipyrone is used in severe pain when no alternative is available

Indications

Dipyrone is primarily indicated in conditions like Biliary colic, Genitourinary tract colic, Headache, Muscular spasm, Neoplasms, Pain, Refractory pyrexia, Rheumatic diseases, Toothache, Trauma, and can also be given in adjunctive therapy as an alternative drug of choice in Surgery.

Contraindications

Dipyrone is contraindicated in conditions like G6pd deficiency, Hepatic porphyria.

Side Effects

The severe or irreversible adverse effects of Dipyrone, which give rise to further complications include Blood dyscrasias, Agranulocytosis, Shock. The symptomatic adverse reactions produced by Dipyrone are more or less tolerable and if they become severe, they can be treated symptomatically, these include Rashes, Urticaria, Asthma, Pain at injection site.

Warnings

Dipyrone should be used with caution in asthmatic patients, in neonates and during pregnancy.

High Risk Groups

Drug should not be given to Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Adult Dosage

0.8 to 1.6 g (1.2 (1.2)) 24 hourly IV/IM — 500 to 1000 mg (750 (750)) 6 hourly PO —

Child Dosage

No child dosage information is recorded for this medicine yet.

Neonatal Dosage

No neonatal dosage information is recorded for this medicine yet.

Drug Interactions

Dipyrone is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementPhenobarbitone These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Storage

Inj,tabs,syrups,drops Store in a well closed container, . Protect from Sunlight and Heat.