Divalproex (Na)

Divalproex (Na) is a synonym of semi sodium valproate (United states approved name USAN), an antiepileptic used particularly in the treatment of primary generalized seizures, and also for partial seizures. Its action are complex and its mode of action is not fully understood. Divalproex (Na) is also used to treat the acute manic attacks and for the prophylaxis of migraine.

Divalproex (Na) is primarily indicated in conditions like Generalized seizures, Partial seizures, Mania, Epilepsy, Migraine prophylaxis.

Divalproex (Na) is contraindicated in conditions like Liver diseases, Urea cycle disorders.

The severe or irreversible adverse effects of Divalproex (Na), which give rise to further complications include Thrombocytopenia, Leucopenia, Bone marrow depression. The symptomatic adverse reactions produced by Divalproex (Na) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Weight gain, Edema, Increased appetite, Nausea, vomiting, Asthenia, Headache, Tremor, Dizziness, Abdominal pain, Diplopia, Diarrhea, Anorexia, Flu syndrome, Fever, Emotional lability, Thinking abnormalities, Alopecia, Weight loss, Constipation, Amnesia.

It should be used with caution in patients with liver disease, bleeding disorder, history of a brain disorder or any allergy. It should be used with caution while driving motor vehicles or performing tasks that require alertness. Before having surgery, including dental surgery, inform the doctor about the use of drug. This may interfere with urine ketone testing and give false positive results, if very high sugar readings (e.g. over 300) are occurring, ketones may be present in urine, contact the doctor or pharmacist. It should be used with extreme caution in children under 2 years old as serious liver problems exist. The drug is not recommended for use during pregnancy or lactation. Treatment should be stopped if pancreatitis is recognized.

If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

750 mg (750 (750)) 24 hourly PO — For mania

No child dosage information is recorded for this medicine yet.

No neonatal dosage information is recorded for this medicine yet.

Divalproex (Na) is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementMephenytoinDivalproex (Na) may interact with Mephenytoin. It can either increase or decrease the effect of Mephenytoin. phenobarbital. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Caps, Tab Store in a well closed container, at room temperature, Between 15°C-25°C. Inj Store at room temperature.