Edetic acid
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
A chelating agent used mainly in the form of its salts for treatment of poisoning by substances such as heavy metals, cyanide, and Organophosphorus compounds. The salts form chelates with metal ions such as lead and mercury and promote the excretion of the metals from the body in a relatively nontoxic form.
Indications
Edetic acid is primarily indicated in conditions like Anticoagulant, and can also be given in adjunctive therapy as an alternative drug of choice in Digitalis induced arrythmias, Hypercalcaemia.
Contraindications
Edetic acid is contraindicated in conditions like Renal diseases,Anuria,Hepatitis,Pregnancy.
Side Effects
Edetic acid produces potentially life-threatening effects which include Cerebral edema, Encephalopathy, Renal tubular damage. which are responsible for the discontinuation of Edetic acid therapy.The signs and symptoms that are produced after the acute overdosage of Edetic acid include Broncho-constriction.
Warnings
Urine flow must be monitored throughout therapy which must be stopped if anuria or severe oliguria develop. The proximal tubule hydropic degeneration usually recovers upon cessation of therapy. Calcium EDTA must be used in reduced doses in patients with pre-existing mild renal disease. Patients should be monitored for cardiac rhythm irregularities and other ECG changes during intravenous therapy.
High Risk Groups
Drug should not be given to Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
No adult dosage information is recorded for this medicine yet.
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Edetic acid is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementInsulinSuccimerConcomitant administration of Succimer with other chelation therapy, such as CaNa2EDTA is not recommended.Zinc These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Storage
No storage information is recorded for this medicine yet.
Available Brands in Pakistan
No brands are recorded for this generic.