Edrophonium (Cl)

Edrophonium injection is used to help diagnose myasthenia gravis (severe muscle weakness) and may be used to help select the proper treatment for the disease. It is also used to reverse the effects of certain muscle relaxants (eg, gallamine, tubocurarine) during surgery or after an overdose of the muscle relaxant. Edrophonium is an anticholinesterase agent. This medicine is to be given only by or under the direct supervision of a doctor.

Edrophonium injection is used to help diagnose myasthenia gravis (severe muscle weakness) and may be used to help select the proper treatment for the disease. It is also used to reverse the effects of certain muscle relaxants (eg, gallamine, tubocurarine) during surgery or after an overdose of the muscle relaxant. Edrophonium is an anticholinesterase agent. This medicine is to be given only by or under the direct supervision of a doctor.

Edrophonium (Cl) is contraindicated in conditions like Intestinal obstruction,Urinary obstruction.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor or nurse immediately if any of the following side effects occur: Incidence not known Chest pain or discomfort dizziness fainting fast, slow, or irregular heartbeat increased frequency of urination increased sweating lightheadedness, dizziness, or fainting loss of bladder control muscle twitches that are visible under the skin seizures slurred speech trouble breathing trouble speaking unusual tiredness Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Incidence not known Abdominal or stomach cramps constricted pupils (black part of the eye) diarrhea double vision hoarseness increased salivation muscle weakness nausea redness of the white part of the eyes or inside of the eyelids sore throat vomiting watering of the eyes Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Edrophonium should be used with caution in patients with asthma, seizure disorder, epilepsy, heart disease such as hypertension, bradycardia, recent myocardial infraction, in thyroid disorders, intestinal disorders, peptic ulcers, urinary problems or if have any allergy especially to bromides. Large dose by mouth should be avoided in condition where there may be increase absorption from the gastrointestinal tract. It is classified as pregnancy category C and should be used only if clearly needed during pregnancy.

Drug should not be given to Pregnant Mothers, Cardiac / Hypertensive Patients, and Neonates. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

0.029 to 0.143 mg/kg (0.086 (0.086)) As recommended. IV — As Required

0.1 mg/kg (0.1 (0.1)) As recommended. Intra Venous — Once in divided doses

0.1 mg/kg (0.1 (0.1)) As recommended. Slow intravenous — Single dose

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Amifampridine Bupropion Donepezil

Inj Store at room temperature. Protect from Sunlight.