Eflornithine

Eflornithine is used in adults and children to keep high-risk neuroblastoma (HRNB), a certain type of cancer , from coming back. Eflornithine is given after prior treatments partially worked. Eflornithine may also be used for purposes not listed in this medication guide.

Eflornithine is used in adults and children to keep high-risk neuroblastoma (HRNB), a certain type of cancer , from coming back. Eflornithine is given after prior treatments partially worked. Eflornithine may also be used for purposes not listed in this medication guide.

Tell your doctor if you have ever had: hearing problems; or low blood cell counts. Eflornithine can harm an unborn baby if the mother or the father is using eflornithine. If you are a woman, you may need a pregnancy test to make sure you are not pregnant. Use birth control while using this medicine and for at least 1 week after your last dose. If you are a man, use birth control if your sex partner is able to get pregnant. Keep using birth control for at least 1 week after your last dose. Tell your doctor right away if a pregnancy occurs. Do not breastfeed while using this medicine, and for at least 1 week after your last dose.

Get emergency medical help if you have signs of an allergic reaction : hives, difficult breathing, swelling of your face, lips, tongue, or throat. Eflornithine may cause serious side effects. Call your doctor at once if you have: hearing problems such as ringing in your ears or hearing loss ; liver problems --loss of appetite, nausea , vomiting , stomach pain (upper right side), tiredness, itching , dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or low blood cell counts -- fever , chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath. Your cancer treatments may change, be delayed, or permanently discontinued if you have certain side effects. Common side effects of eflornithine may include: fever, diarrhea , vomiting; ear, sinus, or skin infections; pneumonia ; urinary infection (UTI); cold or allergy symptoms such as cough , stuffy, runny, or itchy nose, sneezing, sore throat ; or red or swollen eyes (pinkeye). This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

50 mg/kg (50 (50)) As recommended. IV — Scraped Dose — Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Your doctor will perform tests to make sure eflornithine is the right treatment for you. Eflornithine is usually taken twice per day, with or without food. Your doctor will determine the right treatment schedule for you. Swallow the tablet whole. If you cannot swallow a tablet whole, eflornithine can be chewed, or crushed then mixed with soft food or liquid. Read and carefully follow the instructions provided to you on how to prepare and take eflornithine if you are unable to swallow the medicine. Ask your doctor or pharmacist if you don't understand these instructions. Doses are based on body surface area (height and weight). Your dose may change if you gain or lose weight or if you are still growing. You will need frequent medical tests before starting and during treatment, including hearing tests. Your next dose may change or be delayed based on the results. If you vomit shortly after taking eflornithine, do not take another dose. Take your next dose as scheduled. Store at room temperature away from moisture and heat.

No child dosage information is recorded for this medicine yet.

No neonatal dosage information is recorded for this medicine yet.

Other drugs may affect eflornithine, including prescription and over-the-counter medicines, vitamins , and herbal products . Tell your doctor about all other medicines you use.

Inj Store Below 30°C. Do not Freeze. Protect from Sunlight. Inj (reconstituted soln) Store in refrigerator. Do not Freeze. Use within 24 hrs (at 4C) if refrigerated.