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Medicines/Generics/Enoxacin

Enoxacin

Generic medicine reference

Not yet clinically reviewed

This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.

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Overview
Enoxacin is a fluoroquinolone antibiotic. They are relatively non-toxic, well tolerated broad spectrum agents. Their excellent bioavailibilty permits their use for treatment of variety of serious bacterial infections. Enoxacin is antibiotic used to treat infections of the urinary tract and sexually transmitted diseases. It's act by inhibiting DNA gyrase and topoisomerase IV, which are essential enzymes in the reproduction of bacterial DNA.
Indications
Enoxacin is primarily indicated in conditions like Bacterial infections, GI infections, Respiratory tract infections, Skin infections, Soft tissue infections, Urethritis, UTI.
Contraindications
Enoxacin is contraindicated in conditions like Tendinitis, Hypersensitivity to the drug.
Side Effects
The severe or irreversible adverse effects of Enoxacin, which give rise to further complications include Hallucinations, Hallucinations, Eosinophilia, Eosinophilia, Elevated SGPT & SGOT, Seizures, Depression. The symptomatic adverse reactions produced by Enoxacin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Drowsiness, Diarrhea, Anxiety, Tremors, Insomnia, Abdominal pain, Confusion, Photosensitivity, Dyspepsia, Depression, Arthralgia, Nausea and vomiting, Seizures and convulsions.
Warnings
Enoxacin should be used with caution in patient with epilepsy, kidney disease, tendon problems, nervous system disorders, liver disease and of any allergy, including drug allergy. It should be used with caution while driving or performing tasks requiring alertness because it may produce dizziness or lightheadedness. Limit alcohol intake. Photosensitization may occur, so avoid prolonged sun exposure, wear protective clothing and use a sunscreen when outdoors. This medication should be used only when clearly needed during pregnancy or lactation.
High Risk Groups
Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
200 to 400 mg (300 (300)) 12 hourly PO —
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Enoxacin is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementCaffeineFenbufenProbenecidRoflumilastRoflumilast interacts with dual CYP34A/1A2 INHIBITOR like enoxacin and cimetidine where it result in an 59% increase in the roflumilast PDE4 inhibitory effect.TheophyllineTizanidine These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Storage
Tab Store in a well closed container, Below 40°C.

Available Brands in Pakistan

1 active brand listed alphabetically.

ENOXABID

Active

ABBOTT LABORATORIES (PAKISTAN) LIMITED.

DML: ENOXABID

Tabs

8 additional records are present but flagged "Unverified / Legacy" and not listed.