Epoprostenol (Na)
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Epoprostenol is a prostaglandin (a hormone-like substance that occurs naturally in the body). Prostaglandins help to control functions in the body such as blood pressure and muscle contractions.
Epoprostenol is used to treat pulmonary arterial hypertension (PAH) and improve your ability to exercise.
Epoprostenol may also be used for purposes not listed in this medication guide.
Indications
Epoprostenol is a prostaglandin (a hormone-like substance that occurs naturally in the body). Prostaglandins help to control functions in the body such as blood pressure and muscle contractions.
Epoprostenol is used to treat pulmonary arterial hypertension (PAH) and improve your ability to exercise.
Epoprostenol may also be used for purposes not listed in this medication guide.
Contraindications
You should not use epoprostenol if you are allergic to it, or if you have:
fluid in your lungs ( pulmonary edema ); or congestive heart failure caused by a decrease in your heart's ability to pump blood back into the body.
Tell your doctor if you have ever had breathing problems while using epoprostenol.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.
Side Effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Epoprostenol may cause serious side effects. Call your doctor at once if you have:
shortness of breath with dizziness or weakness; a light-headed feeling, like you might pass out; easy bruising, unusual bleeding; or symptoms of pulmonary edema -- anxiety , sweating , pale skin, severe shortness of breath, wheezing , gasping for breath, cough with foamy mucus, chest pain, fast or uneven heart rate.
Common side effects of epoprostenol may include:
flushing (warmth, redness, or tingly feeling); dizziness; nausea , vomiting , diarrhea , stomach pain; trouble breathing; headache , jaw pain; fast or slow heartbeats; joint or muscle pain ; flu-like symptoms; or feeling anxious or nervous.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
You should not use epoprostenol if you have fluid in your lungs, or heart failure caused by a decrease in your heart's ability to pump blood back into the body.
High Risk Groups
You should not use epoprostenol if you have fluid in your lungs, or heart failure caused by a decrease in your heart's ability to pump blood back into the body.
Adult Dosage
2 to 2.5 ng/kg.min (2.2 (2.25)) As recommended. IV Inf — As Required
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Tell your doctor about all your other medicines, especially:
a diuretic or "water pill"; blood pressure medications; or a blood thinner -- warfarin , Coumadin , Jantoven .
This list is not complete. Other drugs may affect epoprostenol, including prescription and over-the-counter medicines, vitamins , and herbal products . Not all possible drug interactions are listed here.
Storage
Inj (reconstituted soln) Store in refrigerator. Do not Freeze. Use within 48 hrs if refrigerated. Vial Store Below 25°C. Do not Freeze. Protect from Sunlight and Moisture.
Available Brands in Pakistan
No brands are recorded for this generic.