This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Etoposide is used to treat small cell lung cancer . It is usually given in combination with other cancer medicines.
Etoposide may also be used for purposes not listed in this medication guide.
Indications
Etoposide is used to treat small cell lung cancer . It is usually given in combination with other cancer medicines.
Etoposide may also be used for purposes not listed in this medication guide.
Contraindications
You should not use etoposide if you are allergic to it.
Tell your doctor if you have ever had kidney disease.
Using etoposide may increase your risk of developing other types of cancer, such as leukemia . Talk with your doctor about your specific risk.
Do not use etoposide if you are pregnant. It could harm the unborn baby. Use effective birth control to prevent pregnancy, and tell your doctor if you become pregnant during treatment.
You should not breastfeed while you are using etoposide.
Side Effects
Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat , burning eyes, skin pain, red or purple skin rash with blistering and peeling).
Etoposide may cause serious side effects. Call your doctor at once if you have:
sudden chest pain or discomfort, wheezing , dry cough or hack; easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin; vision problems; seizure (convulsions); liver problems --loss of appetite, stomach pain (upper right side), tiredness, itching , dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); low red blood cells (anemia) --pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet; or low white blood cell counts --fever, mouth sores, skin sores, sore throat, cough, trouble breathing.
Common side effects of etoposide may include:
sores or white patches in or around your mouth, trouble swallowing or talking, dry mouth , bad breath, altered sense of taste; nausea, vomiting ; or temporary hair loss .
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
Etoposide can increase your risk of bleeding or infection . Call your doctor if you have unusual bruising or bleeding, or new signs of infection (fever, sore throat, trouble breathing).
High Risk Groups
Etoposide can increase your risk of bleeding or infection . Call your doctor if you have unusual bruising or bleeding, or new signs of infection (fever, sore throat, trouble breathing).
Adult Dosage
50 to 120 mg/sq.meter (85 (85)) 24 hourly Slow IV — Over 30-60 Minutes for 5 Days
Child Dosage
Doses not established for this age group ( ) —
Neonatal Dosage
Doses not established for this age group ( ) —
Drug Interactions
Other drugs may affect etoposide, including prescription and over-the-counter medicines, vitamins , and herbal products . Tell your doctor about all your current medicines and any medicine you start or stop using.
Storage
Caps, Inj Store Below 40°C. Protect from Sunlight.
