Flumethasone

Flumethasone is a topical corticosteroid, which is used as creams, ointments or lotions in various skin disorders. It also is used as ear drops in eczematous inflammation in otitis externa.

Flumethasone is primarily indicated in conditions like Inflammatory skin diseases, Inflammation of otitis externa.

Flumethasone is contraindicated in conditions like Invasive salmonellosis.

Side effects such as SAP and SGPT (ALT) enzyme elevations, weight loss, anorexia, polydipsia and polyuria have occurred following parenteral or systemic use of synthetic corticosteroids. In dogs, vomiting and diarrhea, and Cushing’s syndrome have been reported in association with prolonged or repeated steroid therapy. Corticosteroids reportedly cause laminitis in horses.

Clinical and experimental data have demonstrated that corticosteroids administered orally or by injection to animals may induce the first stage of parturition when administered during the last trimester of pregnancy and may precipitate premature parturition followed by dystocia, fetal death, retained placenta and metritis. Additionally, corticosteroids administered to dogs, rabbits and rodents during pregnancy have resulted in cleft palate in offspring. Corticosteroids administered to dogs during pregnancy have also resulted in other congenital anomalies, including deformed forelegs, phocomelia and anasarca.

Clinical and experimental data have demonstrated that corticosteroids administered orally or by injection to animals may induce the first stage of parturition when administered during the last trimester of pregnancy and may precipitate premature parturition followed by dystocia, fetal death, retained placenta and metritis. Additionally, corticosteroids administered to dogs, rabbits and rodents during pregnancy have resulted in cleft palate in offspring. Corticosteroids administered to dogs during pregnancy have also resulted in other congenital anomalies, including deformed forelegs, phocomelia and anasarca.

Scraped Dose — Bimasone is recommended for administration by injection using various routes depending on the animal species and conditions under treatment. Injection should be accomplished slowly, with the drug at or near body temperature. The following recommended dosages should be used as therapeutic guides. Each animal should be treated on an individual basis and dosage adjusted according to the response noted. Dosage of Bimasone: Equine: 1.25 to 2.5 mg daily by intravenous, intramuscular or intra-articular injection. If necessary, the dose may be repeated. Canine: 0.0625 to 0.25 mg daily by intravenous, intramuscular or subcutaneous injection. If necessary, the dose may be repeated. If necessary, the dose may be repeated. With chronic conditions, the preceding doses may be used and oral maintenance therapy with flumethasone tablets instituted at a daily dose of 0.0625 to 0.25 mg. Intralesional dosages in the dog have ranged from 0.125 to 1 mg depending on the size and location of the lesion under treatment. Intra-articular dosages in the dog have ranged from 0.166 to 1 mg depending on the severity of the condition under treatment and the size of the involved joint. Feline: 0.03125 to 0.125 mg by intravenous, intramuscular or subcutaneous injection. If necessary, the dose may be repeated. With chronic conditions, the preceding injectable doses may be used and oral maintenance therapy with flumethasone tablets instituted at a daily dosage of 0.03125 to 0.125 mg. NOTE: The use of a microsyringe or standard tuberculin syringe may facilitate the accurate administration of small amounts of the drug. If desired, therapy with Bimasone may be substituted for other corticoids by the appropriate adjustment of dose levels.

No child dosage information is recorded for this medicine yet.

No neonatal dosage information is recorded for this medicine yet.

Flumethasone is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementLofexidineTheoretical potential for FLUMETASONE reducing the HYPOTENSIVE effect of LOFEXIDINE HYDROCHLORIDE. ModerateMetyrosineTheoretical potential for FLUMETASONE reducing the HYPOTENSIVE effect of METIROSINE. Moderate These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

No storage information is recorded for this medicine yet.