Flutamide

Flutamide is a nonsteroidal antiandrogen (testosterone blocker) medicine. Flutamide capsules are used to treat prostate cancer . Flutamide is given in combination with another medicine called a luteinizing (LOO-tee-in-ize-ing) hormone-releasing hormone, or LHRH. LHRH helps prevent the testicles from producing testosterone.

Flutamide is a nonsteroidal antiandrogen (testosterone blocker) medicine. Flutamide capsules are used to treat prostate cancer . Flutamide is given in combination with another medicine called a luteinizing (LOO-tee-in-ize-ing) hormone-releasing hormone, or LHRH. LHRH helps prevent the testicles from producing testosterone.

You should not use flutamide if you are allergic to it, or if you have severe liver problems. Flutamide should never be taken by a woman or a child. To make sure this medicine is safe for you, tell your doctor if you have ever had: liver disease; a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency; hemoglobin M disease; if you smoke; or if you also take a blood thinner ( warfarin , Coumadin , Jantoven ). Although flutamide is not for use by women, this medicine can cause birth defects if a woman is exposed to it during pregnancy.

Get emergency medical help if you have signs of an allergic reaction to flutamide : hives ; difficult breathing; swelling of your face, lips, tongue, or throat. Flutamide can cause serious liver problems . Call your doctor at once if you have: nausea , upper stomach pain, loss of appetite; itching, tiredness, flu-like symptoms; dark urine, clay-colored stools; or jaundice (yellowing of the skin or eyes). Common flutamide side effects may include: breast swelling or tenderness; hot flashes ; vomiting , nausea, diarrhea; or impotence , loss of interest in sex. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Other drugs may interact with flutamide, including prescription and over-the-counter medicines, vitamins , and herbal products . Tell your doctor about all your current medicines and any medicine you start or stop using.

Flutamide can cause serious liver problems. Call your doctor at once if you have upper stomach pain, itching, tiredness, loss of appetite, dark urine, clay-colored stools, or yellowing of your skin or eyes.

Flutamide can cause serious liver problems. Call your doctor at once if you have upper stomach pain, itching, tiredness, loss of appetite, dark urine, clay-colored stools, or yellowing of your skin or eyes.

250 mg (250 (250)) 8 hourly PO — Scraped Dose — Take flutamide capsules exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Flutamide is usually taken every 8 hours. Follow your doctor's dosing instructions very carefully. Drink plenty of liquids. Your doctor may recommend a special diet to help prevent diarrhea . You will need frequent medical tests. It is recommended you get blood tests: before starting treatment with flutamide, every month for the first 4 months of treatment, and periodically after the first 4 months. Call your doctor if you have severe or ongoing diarrhea. Your doctor may recommend an anti-diarrhea medicine. You should not stop using flutamide suddenly. Stopping suddenly may make your condition worse. Store at room temperature away from moisture, heat, and light.

( ) — Not recommended in this age group

( ) — Not recommended in this age group

Flutamide is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementLeuprolide (Acetate)VORICONAZOLEVoriconazole may increase the serum concentration of flutamide by decreasing its metabolism. Monitor for changes in the therapeutic and adverse effects of flutamide if voriconazole is initiated, discontinued or dose changed.Warfarin (Na) These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Caps Store Below 40°C. Protect from Sunlight and Moisture.