Folinic Acid

Levoleucovorin is used to treat or prevent toxic effects of methotrexate in people who have received methotrexate to treat bone cancer. Levoleucovorin is also used to treat or prevent toxic effects of methotrexate in people whose bodies do not eliminate methotrexate properly after the drug is metabolized. It may also be used to treat toxic effects of an overdose of methotrexate or certain other medications. Levoleucovorin is also used in combination chemotherapy with fluorouracil to treat colorectal cancer that has spread to other parts of the body. Levoleucovorin treats only the symptoms of colorectal cancer but does not treat the cancer itself. Levoleucovorin should not be used to treat anemia that is caused by a lack of vitamin B12.

Levoleucovorin is used to treat or prevent toxic effects of methotrexate in people who have received methotrexate to treat bone cancer. Levoleucovorin is also used to treat or prevent toxic effects of methotrexate in people whose bodies do not eliminate methotrexate properly after the drug is metabolized. It may also be used to treat toxic effects of an overdose of methotrexate or certain other medications. Levoleucovorin is also used in combination chemotherapy with fluorouracil to treat colorectal cancer that has spread to other parts of the body. Levoleucovorin treats only the symptoms of colorectal cancer but does not treat the cancer itself. Levoleucovorin should not be used to treat anemia that is caused by a lack of vitamin B12.

You should not receive this medicine if you are allergic to levoleucovorin, folic acid, or folinic acid. If possible, before you receive levoleucovorin, tell your doctor or caregivers if you have: kidney disease; or if you are dehydrated. It is not known whether levoleucovorin will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. It may not be safe to breastfeed while using levoleucovorin. Ask your doctor about any risk. In an emergency, you may not be able to tell caregivers if you are pregnant or breast feeding. Make sure any doctor caring for your pregnancy or your baby knows you received this medicine.

Get emergency medical help if you have any signs of an allergic reaction to levoleucovorin: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Tell your doctor or caregivers at once if you have: blisters or ulcers in your mouth, red or swollen gums, trouble swallowing; severe or ongoing diarrhea; a light-headed feeling, like you might pass out; seizure (convulsions); dehydration symptoms - feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin; or kidney problems - little or no urination; painful or difficult urination; swelling in your feet or ankles. Common levoleucovorin side effects may include: diarrhea, nausea, vomiting; or pain or sores in your mouth. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

You should not be treated with this medication if you are allergic to levoleucovorin or to folic acid or folinic acid. Tell your doctor if you are taking sulfa drugs, seizure medication, a cancer medication called fluorouracil (5FU), or a multivitamin or mineral supplement than contains folic acid. In an emergency situation, it may not be possible before you are treated to tell your caregivers about all of your medical conditions or if you are pregnant or breast-feeding. However, make sure any doctor caring for you afterward knows that you have received levoleucovorin. Tell your doctor or caregivers at once if you have fever, chills, white patches or sores inside your mouth or on your lips, severe or ongoing diarrhea, confusion, urination problems, or if you feel very thirsty or hot, if you are unable to urinate, and you have heavy sweating or hot and dry skin.

You should not be treated with this medication if you are allergic to levoleucovorin or to folic acid or folinic acid. Tell your doctor if you are taking sulfa drugs, seizure medication, a cancer medication called fluorouracil (5FU), or a multivitamin or mineral supplement than contains folic acid. In an emergency situation, it may not be possible before you are treated to tell your caregivers about all of your medical conditions or if you are pregnant or breast-feeding. However, make sure any doctor caring for you afterward knows that you have received levoleucovorin. Tell your doctor or caregivers at once if you have fever, chills, white patches or sores inside your mouth or on your lips, severe or ongoing diarrhea, confusion, urination problems, or if you feel very thirsty or hot, if you are unable to urinate, and you have heavy sweating or hot and dry skin.

120 mg (120 (120)) As recommended. IV,IM — In div.doses over 12-24 hrs.

No child dosage information is recorded for this medicine yet.

No neonatal dosage information is recorded for this medicine yet.

Tell your doctor about all medicines you use, and those you start or stop using during your treatment with levoleucovorin, especially: seizure medicine - phenobarbital, phenytoin, primidone; a multivitamin or mineral supplement than contains folic acid; or a sulfa drug (Bactrim, Septra, Sulfatrim, SMX-TMP or SMZ-TMP, and others). This list is not complete. Other drugs may interact with levoleucovorin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Tab, Inj Store Below 40°C. Protect from Sunlight and Heat.