Formestane
Generic medicine reference
Overview
Formestane is a steroidal, selective aromatase inhibitor which is used in the treatment of estrogen receptor-positive breast cancer in postmenopausal women.
Indications
Formestane is primarily indicated in conditions like Breast cancer.
Contraindications
Formestane is contraindicated in conditions like Premenopausal breast cancer.
Side Effects
The severe or irreversible adverse effects of Formestane, which give rise to further complications include Vaginal bleeding. Formestane produces potentially life-threatening effects which include Anaphylaxis. which are responsible for the discontinuation of Formestane therapy. The symptomatic adverse reactions produced by Formestane are more or less tolerable and if they become severe, they can be treated symptomatically, these include Skin reactions, Bone pain, Arthralgia, Muscle cramps, Hot flushes, Dizziness, Drowsiness, GI disturbance, Vasovagal reaction, Edema of legs, Thrombophlebitis.
Warnings
Formestane is not recommended for use during pregnancy or lactation. Immunosuppressant drug should not be given, where possible, to patients with acute infection, dosage reduction or withdrawal should be considered if infection develops, until the infection has been controlled. Blood counts and measurement of hemoglobin concentration should be carried out routinely, it helps to predict the onset of bone marrow depression. It must be handled with great care and avoid contact with skin and eyes, and should not be inhaled.
High Risk Groups
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
3.571 mg/kg (3.6 (3.571)) As recommended. IM — Fortnightly
Child Dosage
( ) — Not recommended in this age group
Neonatal Dosage
( ) — Not recommended in this age group
Drug Interactions
No data regarding the interactions of Formestane was found.
Storage
Inj (reconstituted susp) Store in refrigerator. Use within 24 hrs if kept at room temperature. Vial Store at room temperature.
Available Brands in Pakistan
No brands are recorded for this generic.
For educational purposes only. Check current guidelines and consult a qualified healthcare professional before making clinical decisions.