Medicines/Generics/Fosfomycin

Fosfomycin

Generic medicine reference

Not yet clinically reviewed

This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.

Spot an error in this entry? Submit a correction

Overview

Fosfomycin is an antibiotic that fights bacterial infections in the urinary tract. It is available in two formulations: Granules for oral solution (Monurol, generic) : Used for uncomplicated bladder infections in women Intravenous infusion (Contepo) : Used for complicated urinary tract infections in adults 18 years and older. Both forms work against common bacteria that cause urinary tract infections, including Escherichia coli ( E. coli ).

Indications

Contraindications

Fosfomycin is contraindicated in conditions like Hypersensitivity to the drug.

Side Effects

The symptomatic adverse reactions produced by Fosfomycin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Nausea, Diarrhea, Vaginitis, Asthenia, Increased intracranial pressure, Anorexia, Epigastric discomfort, Pruritus.

Warnings

Fosfomycin should be used with caution in patients with medical history, including any allergy, especially drug allergy or kidney disease. It should be used with caution during pregnancy and not recommended during lactation. Caution is advised for use in females under 18 years old.

High Risk Groups

Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Adult Dosage

1 g (1 (1)) 8 hourly IM — 1 to 4 g (2.5 (2.5)) 8 hourly IV — 3 g (3 (3)) As recommended. PO — As a single dose or 2 div.doses.

Child Dosage

100 to 200 mg/kg (150 (150)) 8 hourly Intra Venous — - 25 mg/kg (25 (25)) 6 hourly Oral — - 50 mg/kg (50 (50)) 8 hourly Intra Muscular — -

Neonatal Dosage

100 to 400 mg/kg (250 (250)) 24 hourly Intravenous — 31.25 mg/kg (31 (31.25)) 12 hourly Intramuscular —

Drug Interactions

Fosfomycin is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementCefotaximesynergestic effect aganist methicillin resistant staphylococci.Metoclopramide (HCl) These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Storage

Powder Store in a well closed container, Below 40°C. Protect from Sunlight and Moisture.

Available Brands in Pakistan

27 active brands listed alphabetically.

Fosfomycin

Available Brands in Pakistan

BIOFOS

CYNFO

EFOMYCIN

FACTUM

FASFOCIN

FISMIN

FOCIN

FOFY

FOSAV

FOSAV DS

FOSFIN

FOSFOMYCIN

FOSFOMYCIN

FOSFOMYCIN

FOSFOMYCIN

FOSFOMYCIN

FOSFOMYCIN

FOSFOMYCIN CHINA

FOSFOMYCIN SPAIN

Fosival

FOSME

FOSOMIN

FOSORIL

MIFOS

MONUROL

OB-FOSFO-5

SONOMYCIN