This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Furazolidone is used to treat bacterial and protozoal infections. It works by killing bacteria and protozoa (tiny, one-celled animals). Some protozoa are parasites that can cause many different kinds of infections in the body.
Furazolidone is taken by mouth. It works inside the intestinal tract to treat cholera, colitis, and/or diarrhea caused by bacteria, and giardiasis. This medicine is sometimes given with other medicines for bacterial infections.
Furazolidone may cause some serious side effects when taken with certain foods, beverages, or other medicines. Check with your health care professional for a list of products that should be avoided.
Furazolidone is available only with your doctor's prescription.
Indications
Furazolidone is used to treat bacterial and protozoal infections. It works by killing bacteria and protozoa (tiny, one-celled animals). Some protozoa are parasites that can cause many different kinds of infections in the body.
Furazolidone is taken by mouth. It works inside the intestinal tract to treat cholera, colitis, and/or diarrhea caused by bacteria, and giardiasis. This medicine is sometimes given with other medicines for bacterial infections.
Furazolidone may cause some serious side effects when taken with certain foods, beverages, or other medicines. Check with your health care professional for a list of products that should be avoided.
Furazolidone is available only with your doctor's prescription.
Contraindications
Furazolidone is contraindicated in conditions like G6pd deficiency.
Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Rare
Fever itching joint pain skin rash or redness sore throat
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
Abdominal or stomach pain diarrhea headache nausea or vomiting
This medicine commonly causes dark yellow to brown discoloration of urine. This side effect does not usually need medical attention.
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Chemical Class: Nitrofuran
Warnings
Furazolidone should be used with caution in patients with medical history, especially of blood disorders, glucose-6-phosphate dehydrogenase (G6PD) deficiency or allergies, especially of drug allergies. Avoid intake of alcohol during therapy and for 4 days after taking this medication. The following are among the foods and beverages to be avoided while taking this medication and for 2 weeks after stop. These foods interact with monoamine oxidase (MAO) inhibitors causing severe headache and increased blood pressure and could lead to a medical emergency, so use with caution while taking meat, fish, pickled herring, liver, dry sausage, meats prepared with tenderizer, yogurt, sour cream, cheese, beverages, avoid excessive amounts of caffeine containing colas, coffee and tea, fruits or vegetables, bananas, figs, raisins, broad beans, yeast extract, soya sauce, large amounts of chocolate. This medication should be used only if clearly needed during pregnancy or lactation. Infants less than one month old should not receive this drug. The drug also inhibit some enzymes including monoamine oxidase. The urine of the patient on furazolidone may be colored a dark yellow or brown ; this results from the presence of metabolites and is not harmful.
High Risk Groups
Drug should not be given to Pregnant Mothers, Geriatrics, and Neonates. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
25 to 50 mg (38 (37.5)) 6 hourly PO — For 7-10 Days
Child Dosage
1.25 mg/kg (1.2 (1.25)) 6 hourly Oral — For Paeds of all ages
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Amitriptyline Amphetamine Apraclonidine Benzphetamine Brimonidine Bupropion Carbamazepine Carbidopa Carbinoxamine Clomipramine Clovoxamine Codeine Cyclobenzaprine Cyproheptadine Desipramine Deutetrabenazine Dextroamphetamine Dextromethorphan Diethylpropion Doxylamine Entacapone Femoxetine Fenfluramine Guanadrel Guanethidine Hydroxytryptophan Imipramine Isocarboxazid Levodopa Levomethadyl Lisdexamfetamine Maprotiline Mazindol Meperidine Methamphetamine Methyldopa Mirtazapine Nefazodone Nefopam Nortriptyline Opipramol Ozanimod Phendimetrazine Phenmetrazine Phentermine Phenylalanine Pseudoephedrine Reserpine Safinamide Selegiline Sertraline Sibutramine Solriamfetol Sumatriptan Tetrabenazine Tramadol Tranylcypromine Trimipramine Tryptophan Venlafaxine Viloxazine Zimeldine
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Alfentanil Benzhydrocodone Butorphanol Cholera Vaccine, Live Difenoxin Dihydrocodeine Diphenoxylate Dolasetron Droperidol Epinephrine Ethchlorvynol Fentanyl Frovatriptan Granisetron Guarana Hydrocodone Hydromorphone Iobenguane I 123 Iobenguane I 131 Kava Lasmiditan Levorphanol Licorice Lithium Lorcaserin Ma Huang Mate Metaraminol Metaxalone Methadone Methylene Blue Metoclopramide Midodrine Morphine Morphine Sulfate Liposome Naratriptan Norepinephrine Ondansetron Oxycodone Oxymetazoline Oxymorphone Palonosetron Pentazocine Phenylephrine Phenylpropanolamine Reboxetine Remifentanil St John's Wort Sufentanil Tyrosine Ziprasidone
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Ginseng
Storage
Tab Store in a well closed container, Between 15°C-30°C. Protect from Sunlight. Syrup Store at room temperature, Between 15°C-30°C. Do not Freeze. Protect from Sunlight.