Furosemide
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Furosemide is a loop diuretic used to treat fluid retention ( edema ) in people with congestive heart failure , liver disease, or a chronic kidney disorder such as nephrotic syndrome. Furosemide is also used to treat high blood pressure (hypertension).
Furosemide works by increasing the amount of urine the body makes, which helps reduce swelling and symptoms of fluid retention and helps lower high blood pressure. Furosemide tablets are sometimes called water pills as they increase how much you urinate.
Furosemide is also known as frusemide in some countries. Furosemide became an FDA-approved medicine on July 1, 1966, and is available as tablets (Lasix), oral liquid, a subcutaneous injection (Furoscix, Lasix ONYU), and an intravenous solution.
Indications
Furosemide is a loop diuretic used to treat fluid retention ( edema ) in people with congestive heart failure , liver disease, or a chronic kidney disorder such as nephrotic syndrome. Furosemide is also used to treat high blood pressure (hypertension).
Furosemide works by increasing the amount of urine the body makes, which helps reduce swelling and symptoms of fluid retention and helps lower high blood pressure. Furosemide tablets are sometimes called water pills as they increase how much you urinate.
Furosemide is also known as frusemide in some countries. Furosemide became an FDA-approved medicine on July 1, 1966, and is available as tablets (Lasix), oral liquid, a subcutaneous injection (Furoscix, Lasix ONYU), and an intravenous solution.
Contraindications
You should not use furosemide if you are allergic to it, are unable to urinate, or have hepatic cirrhosis .
To make sure furosemide is safe for you, tell your doctor if you have ever had:
an electrolyte imbalance (such as low levels of potassium or magnesium in your blood); enlarged prostate , bladder obstruction, or other urination problems; gout ; lupus ; diabetes; an allergy to sulfa drugs ; kidney disease; or cirrhosis or other liver disease.
Tell your doctor if you have an MRI (magnetic resonance imaging) or any type of scan using a radioactive dye that is injected into a vein. Contrast dyes and furosemide can harm your kidneys.
Furoscix is a subcutaneous infusion of furosemide which is administered at home by you or your caregiver with the use of the Furoscix On-Body Infusor. It is used to treat edema in children weighing 43 kg (94.7 lb) or more and adults with chronic heart failure or chronic kidney disease, including the nephrotic syndrome.
Lasix ONYU is a pre-programmed infusor containing furosemide that is FDA approved for the treatment of edema in adults with chronic heart failure (HF).
Side Effects
Common furosemide side effects may include:
diarrhea , constipation, loss of appetite; numbness or tingling; headache , dizziness; or blurred vision.
Serious furosemide side effects
Get emergency medical help if you have signs of an allergic reaction to furosemide (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction ( fever , sore throat , burning eyes, skin pain, red or purple skin rash with blistering and peeling).
Furosemide may cause other serious side effects. Call your doctor at once if you have:
a light-headed feeling, like you might pass out; ringing in your ears, hearing loss; muscle spasms or contractions; pale skin, easy bruising, unusual bleeding; high blood sugar - increased thirst, increased urination, dry mouth, fruity breath odor; kidney problems - swelling, urinating less, feeling tired or short of breath signs of liver or pancreas problems - loss of appetite, upper stomach pain (that may spread to your back), nausea or vomiting , dark urine, jaundice (yellowing of the skin or eyes); or signs of an electrolyte imbalance - increased thirst or urination, constipation , muscle weakness, leg cramps, numbness or tingling, feeling jittery, fluttering in your chest.
This is not a complete list of side effects, and others may occur. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Warnings
You should not use furosemide if you are unable to urinate.
Using more than your recommended dose will not make this medicine more effective. High doses of this medicine may cause irreversible hearing loss .
Before using this medicine, tell your doctor if you have kidney disease, enlarged prostate, urination problems, cirrhosis or other liver disease, an electrolyte imbalance, high cholesterol, gout, lupus, diabetes, or an allergy to sulfa drugs.
Tell your doctor if you have recently had an MRI (magnetic resonance imaging) or any type of scan using a radioactive dye that is injected into your veins. Do not take more of this medication than is recommended.
If you are being treated for high blood pressure, keep using this medicine even if you feel fine. High blood pressure often has no symptoms.
Furosemide is a potent diuretic which, if given in excessive amounts, can lead to a profound diuresis with water and electrolyte depletion. Therefore, careful medical supervision is required and the dose schedule must be adjusted to the individual patient’s needs
Tell your doctor about all your other medicines. Some drugs should not be used with furosemide.
High Risk Groups
You should not use furosemide if you are unable to urinate.
Using more than your recommended dose will not make this medicine more effective. High doses of this medicine may cause irreversible hearing loss .
Before using this medicine, tell your doctor if you have kidney disease, enlarged prostate, urination problems, cirrhosis or other liver disease, an electrolyte imbalance, high cholesterol, gout, lupus, diabetes, or an allergy to sulfa drugs.
Tell your doctor if you have recently had an MRI (magnetic resonance imaging) or any type of scan using a radioactive dye that is injected into your veins. Do not take more of this medication than is recommended.
If you are being treated for high blood pressure, keep using this medicine even if you feel fine. High blood pressure often has no symptoms.
Furosemide is a potent diuretic which, if given in excessive amounts, can lead to a profound diuresis with water and electrolyte depletion. Therefore, careful medical supervision is required and the dose schedule must be adjusted to the individual patient’s needs
Tell your doctor about all your other medicines. Some drugs should not be used with furosemide.
Adult Dosage
No adult dosage information is recorded for this medicine yet.
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Sometimes it is not safe to use certain medicines at the same time. Some drugs can affect your blood levels of other drugs you use, which may increase side effects or make the medicines less effective
If you also take sucralfate , take your furosemide dose 2 hours before or 2 hours after you take sucralfate.
Tell your doctor about all your other medicines, especially:
another diuretic, especially ethacrynic acid ; methotrexate ; chloral hydrate ; lithium ; phenytoin ; an antibiotic ; cancer medicine, such as cisplatin ; heart or blood pressure medicine; or NSAIDs (nonsteroidal anti-inflammatory drugs) - aspirin , ibuprofen ( Advil , Motrin ), naproxen ( Aleve ), celecoxib , diclofenac , indomethacin , meloxicam , and others.
This list is not complete. Other drugs may interact with furosemide, including prescription and over-the-counter medicines, vitamins , and herbal products . Not all possible drug interactions are listed here.
Storage
No storage information is recorded for this medicine yet.
Available Brands in Pakistan
7 active brands listed alphabetically.
DRUSIX
ActiveBOSCH PHARMACEUTICALS (PVT) LTD.
DML: DRUSIX
Inj
FRUSEMIDE
ActiveBajwa Pharmaceuticals (Pvt.) Ltd. DML: 000805
DML: FRUSEMIDE
Inj
G-MIDE
ActiveGETZ PHARMA PAKISTAN (PVT) LTD.
DML: G-MIDE
Tabs
MUSEM
ActiveMISSION PHARMACEUTICALS
DML: MUSEM
Tabs
OEDEMIN
ActiveMEDIPAK LIMITED
DML: OEDEMIN
Inj
URISIDE
ActiveNABIQASIM INDUSTRIES (PVT) LTD.
DML: URISIDE
Tabs
WETREX
ActiveSHAIGAN PHARMACEUTICALS (PVT) LTD.
DML: WETREX
Tabs
