Gemfibrozil
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Gemfibrozil helps reduce cholesterol and triglycerides (fatty acids) in the blood. High levels of these types of fat in the blood are associated with an increased risk of atherosclerosis (clogged arteries).
Gemfibrozil is used together with diet to treat very high cholesterol and triglyceride levels in people with pancreatitis .
Gemfibrozil is also used to lower the risk of stroke, heart attack , or other heart complications in certain people with high cholesterol and triglycerides who have not been helped by other treatment methods.
Indications
Gemfibrozil helps reduce cholesterol and triglycerides (fatty acids) in the blood. High levels of these types of fat in the blood are associated with an increased risk of atherosclerosis (clogged arteries).
Gemfibrozil is used together with diet to treat very high cholesterol and triglyceride levels in people with pancreatitis .
Gemfibrozil is also used to lower the risk of stroke, heart attack , or other heart complications in certain people with high cholesterol and triglycerides who have not been helped by other treatment methods.
Contraindications
You should not use gemfibrozil if you are allergic to it, if you have:
severe liver disease; severe kidney disease; gallbladder disease; or if you are also taking repaglinide, dasabuvir, or simvastatin.
To make sure gemfibrozil is safe for you, tell your doctor if you have ever had::
gallstones ; or if you also take warfarin ( Coumadin , Jantoven ).
It is not known whether gemfibrozil will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.
Side Effects
Get emergency medical help if you have signs of an allergic reaction to gemfibrozil: hives ; difficulty breathing; swelling of your face, lips, tongue, or throat.
In rare cases, gemfibrozil can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure . Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.
Also call your doctor at once if you have:
sharp pain in your upper stomach (especially after eating); jaundice (yellowing of your skin or eyes); pain or burning when you urinate; blurred vision, eye pain, or seeing halos around lights; or low blood cell counts - pale skin, easy bruising, unusual bleeding, unusual tiredness, feeling light-headed or short of breath, cold hands and feet.
Common gemfibrozil side effects may include:
stomach pain, indigestion , diarrhea ; numbness or tingly feeling; dizziness , drowsiness; blurred vision; muscle or joint pain; or loss of interest in sex, impotence .
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
You should not take gemfibrozil if you have severe liver or kidney disease, gallbladder disease , or if you are also taking repaglinide , dasabuvir, or simvastatin .
High Risk Groups
You should not take gemfibrozil if you have severe liver or kidney disease, gallbladder disease , or if you are also taking repaglinide , dasabuvir, or simvastatin .
Adult Dosage
600 mg (600 (600)) 12 hourly PO —
Scraped Dose — Take gemfibrozil exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.
Gemfibrozil is usually taken 30 minutes before breakfast and dinner. Follow your doctor's dosing instructions very carefully.
Gemfibrozil is only part of a complete treatment program that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.
You may need frequent medical tests. Even if you have no symptoms, tests can help your doctor determine if this medicine is effective.
Store at room temperature away from moisture, heat, and light.
Child Dosage
( ) — Not recommended in this age group
Neonatal Dosage
( ) — Not recommended in this age group
Drug Interactions
Using certain medicines together with gemfibrozil can increase your risk of serious muscle problems. It is very important to tell your doctor about all medicines you use, and those you start or stop using, especially:
colchicine ; or a "statin" cholesterol-lowering medicine - atorvastatin , fluvastatin , lovastatin , pitavastatin , pravastatin , rosuvastatin , simvastatin, Crestor , Lipitor , Zocor , Vytorin , and others.
This list is not complete and many other drugs may interact with gemfibrozil. This includes prescription and over-the-counter medicines, vitamins , and herbal products . Not all possible drug interactions are listed here.
Storage
Tab, Caps Store in a well closed container, at room temperature, Below 30°C.
Available Brands in Pakistan
1 active brand listed alphabetically.
GEMPID
ActiveATCO LABORATORIES LIMITED
DML: GEMPID
Caps
2 additional records are present but flagged "Unverified / Legacy" and not listed.
