Gestrinone
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Gestrinone is a synthetic steroidal hormone that exhibits androgenic, anti-estrogenic and anti-progestogenic properties. It reduces the size of endometrial tissue fragments and leads to their regression, therefore Gestrinone is used mainly for treatment of endometriosis. It may inhibit ovulation and menstrual irregularities such as breakthrough bleeding may occur during treatment.
Indications
Gestrinone is primarily indicated in conditions like Endometriosis, and can also be given in adjunctive therapy as an alternative drug of choice in Benign breast disease, Fibroids, Intracranial meningiomas, Menorrhagia.
Contraindications
Gestrinone is contraindicated in conditions like Cardiac insufficiency, Pregnancy, Lactation, Metabolic or vascular disorders, Renal insufficiency, Hepatic insufficiency.
Side Effects
The symptomatic adverse reactions produced by Gestrinone are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Nervousness, Cramps, Depression, Weight gain, Fluid retention, Hot flushes, Acne, Hirsutism, Changes in libido, GI disturbance, Oily skin, Voice changes, Light vaginal bleeding, Irregular bleeding, Deepening of voice.
Warnings
It should not be used during pregnancy or lactation. It should be used with caution in-patients with migraine headaches, heart, liver or kidney disease, a history of seizures, breast cancer, abnormal bleeding, previous strokes, prostate cancer or any other diseases. Extreme caution is advised for use in children. Pediatric specialist consultation is also advised. Geriatric men are at increased risk of developing enlarged prostate and prostate cancer with the use of androgen-like drugs, so use cautiously.
High Risk Groups
Drug should not be given to Pediatrics, Pregnant Mothers, Cardiac / Hypertensive Patients, patients suffering from Kidney dysfunction, and Neonates. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
No adult dosage information is recorded for this medicine yet.
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
No data regarding the interactions of Gestrinone was found.
Storage
Store Below 30°C. Caps Store Below 25°C. Protect from Sunlight.
Available Brands in Pakistan
No brands are recorded for this generic.