Glycopyrrolate
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Glycopyrrolate helps to control conditions such as peptic ulcers that involve excessive stomach acid production.
Glycopyrrolate is also used to reduce drooling in children ages 3 to 16 who have certain medical conditions, such as cerebral palsy .
Glycopyrrolate injection is also used during surgery to reduce secretions in your stomach or airway, and to help protect your heart and nervous system while you are under general anesthesia .
Glycopyrrolate may also be used for purposes not listed in this medication guide.
Indications
Glycopyrrolate helps to control conditions such as peptic ulcers that involve excessive stomach acid production.
Glycopyrrolate is also used to reduce drooling in children ages 3 to 16 who have certain medical conditions, such as cerebral palsy .
Glycopyrrolate injection is also used during surgery to reduce secretions in your stomach or airway, and to help protect your heart and nervous system while you are under general anesthesia .
Glycopyrrolate may also be used for purposes not listed in this medication guide.
Contraindications
You should not use glycopyrrolate if you are allergic to it, or if you have:
a bladder obstruction or other urination problems; a stomach or bowel obstruction (including paralytic ileus ); severe constipation; severe ulcerative colitis or toxic megacolon; glaucoma; myasthenia gravis; or active bleeding with fast heartbeats, low blood pressure , shortness of breath , and cold hands or feet.
Tell your doctor if you have ever had:
an enlarged prostate ; liver or kidney disease; heart problems or a heart rhythm disorder; high blood pressure ; a stomach disorder such as ulcerative colitis, hiatal hernia , reflux disease, or slow digestion; a colostomy or ileostomy; a thyroid disorder; or a nerve disorder.
It is not known whether glycopyrrolate will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
You should not breastfeed while using glycopyrrolate. Glycopyrrolate may slow breast milk production.
Do not give this medicine to a child without medical advice.
Side Effects
Get emergency medical help if you have signs of an allergic reaction : hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Glycopyrrolate may cause serious side effects. Stop using glycopyrrolate and call your doctor at once if you have:
severe constipation , severe stomach pain and bloating; diarrhea (especially if you have a colostomy or ileostomy); painful or difficult urination; fast or pounding heartbeats, fluttering in your chest; confusion, severe drowsiness; eye pain, seeing halos around lights; fever, shallow breathing, weak pulse, hot and red skin; or (in a child taking glycopyrrolate) dry diapers, fussiness, or excessive crying.
Common side effects of glycopyrrolate may include:
constipation, nausea, vomiting, bloating; drowsiness, dizziness, weakness, feeling nervous; slow or fast heartbeats; sleep problems (insomnia); flushing (sudden warmth, redness, or tingly feeling); blurred vision, sensitivity to light; dry mouth, decreased sense of taste; decreased sweating, decreased urination; impotence, sexual problems; headache; or rash.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
You should not use glycopyrrolate if you have urination problems, a blockage in your stomach or intestines, severe constipation, severe ulcerative colitis or toxic megacolon, glaucoma, myasthenia gravis , or active bleeding with heart and blood circulation problems.
High Risk Groups
You should not use glycopyrrolate if you have urination problems, a blockage in your stomach or intestines, severe constipation, severe ulcerative colitis or toxic megacolon, glaucoma, myasthenia gravis , or active bleeding with heart and blood circulation problems.
Adult Dosage
10 to 15 ug/ kg Neostigmine (12 (12.5)) As recommended. IV — For control of Muscranic side effects of Neostigmine in reversal of competitive neuromuscular block
2 to 3 mg (2.5 (2.5)) 8 hourly PO — For Hyperhidrosis
200 to 400 ug (300 (300)) As recommended. IM,IV — As Premedication
Child Dosage
4.4 to 8.8 ug/kg (6.6 (6.6)) As recommended. Intra Muscular — 0.5-1 hr before induction of anaesthesia, as required . To maximum of 200 ug.
4.4 to 8.8 ug/kg (6.6 (6.6)) As recommended. Intra Venous — 0.5-1 hr before induction of anaesthesia, as required
Neonatal Dosage
4.4 to 8.8 ug/kg (6.6 (6.6)) As recommended. Intra Muscular — 0.5-1 hr before induction of anaesthesia, as required
4.4 to 8.8 ug/kg (6.6 (6.6)) As recommended. Intra Venous — 0.5-1 hr before induction of anaesthesia, as required
Drug Interactions
Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.
Tell your doctor about all your other medicines, especially:
medicine to treat depression , anxiety, mood disorders, or mental illness; opioid medication; sleep medicine, cold or allergy medicine (Benadryl and others); medicine to treat Parkinson's disease ; medicine to treat stomach problems, motion sickness , or irritable bowel syndrome ; medicine to treat overactive bladder ; bronchodilator asthma medication; or seizure medication.
This list is not complete. Other drugs may affect glycopyrrolate, including prescription and over-the-counter medicines, vitamins, and herbal products . Not all possible drug interactions are listed here.
Storage
Tab Store in a well closed container, Below 40°C. Protect from Sunlight and Moisture.
Available Brands in Pakistan
No active brands are currently recorded for this generic.
1 record is present but flagged "Unverified / Legacy" and excluded.
