Gonadotropin
Generic medicine reference
Overview
Gonadotropin is a hormone. Gonadotropin is used in the treatment of infertility in men and women. It stimulates the ovaries and the testes. Gonadotropin is used in males to stimulate testicular descent or testicular growth and development. In females, Gonadotropin is used in combination with other drugs to induce ovulation. It is a hormone produced by placenta & obtained from the urine of pregnant women.
Indications
Gonadotropin is primarily indicated in conditions like Cryptorchidism, Hypogonadotropic hypogonadism, Induction of ovulation, Infertility.
Contraindications
Gonadotropin is contraindicated in conditions like Prostatic cancer, Hypersensitivity to any component of product.
Side Effects
The severe or irreversible adverse effects of Gonadotropin, which give rise to further complications include Ovarian enlargement, Gynecomastia, Shock. The symptomatic adverse reactions produced by Gonadotropin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Tinnitus, Hypersensitivity reactions, Depression, Edema, Mood swings, Acute Abdominal pain.
Warnings
Gonadotropin should not be used during pregnancy. It should be used with caution in patients with history of heart disease, kidney disease, asthma, migraine headaches, seizure disorder, cancer or any allergies. It should not be given in carcinoma of prostate or precocious puberty & in presence of breast uterine & testicular as well as tumors of hypothalamus pituitary thyroid & adrenal glands.
High Risk Groups
Drug should not be given to Pregnant Mothers. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
2.5 to 5 ug/ kg.min (3.8 (3.75)) As recommended. IV Inf — Initially, As Required
20 to 50 ug/ kg.min (35 (35)) As recommended. IV Inf — Maintenance, increased gradually, As Required
5000 to 10000 IU (7500 (7500)) As recommended. IM —
Child Dosage
( ) — Not recommended in this age group
Neonatal Dosage
( ) — Not recommended in this age group
Drug Interactions
No data regarding the interactions of Gonadotropin was found.
Storage
Store in a well closed container, Below 15°C. Protect from Sunlight.
Available Brands in Pakistan
2 active brands listed alphabetically.
IVF-C
ActiveGALAXY PHARMA (PVT) LTD.
DML: IVF-C
Inj
IVF-M
ActiveGALAXY PHARMA (PVT) LTD.
DML: IVF-M
Inj
For educational purposes only. Check current guidelines and consult a qualified healthcare professional before making clinical decisions.