Human Insulin

Insulin glargine is a long-acting insulin used to treat type 1 and type 2 diabetes in certain patients to improve and maintain blood glucose levels. Insulin glargine is a man-made form of human insulin that is used once daily to provide a base level of insulin that keeps working for 24 hours or longer. Insulin glargine is available under the brand names Lantus , Basaglar , Toujeo, Semglee , and Rezvoglar . Rezvoglar, Lantus, Semglee, and Toujeo are FDA-approved to be used for use in adult and pediatric patients with type 1 and type 2 diabetes. Basasglar is FDA-approved to be used by adults for type 2 diabetes and also for adults and pediatric patients with type 1 diabetes . In patients with type 1 diabetes, insulin glargine must be used together with a short-acting insulin.

Insulin glargine is a long-acting insulin used to treat type 1 and type 2 diabetes in certain patients to improve and maintain blood glucose levels. Insulin glargine is a man-made form of human insulin that is used once daily to provide a base level of insulin that keeps working for 24 hours or longer. Insulin glargine is available under the brand names Lantus , Basaglar , Toujeo, Semglee , and Rezvoglar . Rezvoglar, Lantus, Semglee, and Toujeo are FDA-approved to be used for use in adult and pediatric patients with type 1 and type 2 diabetes. Basasglar is FDA-approved to be used by adults for type 2 diabetes and also for adults and pediatric patients with type 1 diabetes . In patients with type 1 diabetes, insulin glargine must be used together with a short-acting insulin.

You should not use insulin glargine if you are allergic to insulin, or if you are having an episode of hypoglycemia (low blood sugar) or diabetic ketoacidosis (call your doctor for treatment). Different brands of insulin glargine are specifically approved for different age groups and different diabetes types. The safety and effectiveness of insulin glargine in pediatric patients younger than 6 years of age with type 1 diabetes and pediatric patients with type 2 diabetes has not been established. Tell your doctor if you have ever had: liver or kidney disease; or heart failure or other heart problems. Tell your doctor if you also take pioglitazone or rosiglitazone (sometimes contained in combinations with glimepiride or metformin). Taking certain oral diabetes medicines while you are using insulin may increase your risk of serious heart problems.

Common insulin glargine side effects may include low blood sugar , swelling, weight gain, allergic reaction, itching, rash, or thickening or hollowing of the skin where you injected the medicine (lipodystrophy). Serious insulin glargine side effects Get emergency medical help if you have signs of insulin allergy: redness or swelling where an injection was given, itchy skin rash over the entire body, trouble breathing, fast heartbeats, feeling like you might pass out, or swelling in your tongue or throat. Insulin glargine may cause other serious side effects. Call your doctor at once if you have: rapid weight gain, swelling in your feet or ankles; shortness of breath ; or low blood potassium--leg cramps, constipation , irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling. This is not a complete list of side effects, and others may occur. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Never share an injection pen, even if you changed the needle.

Never share an injection pen, even if you changed the needle.

0.05 to 0.2 IU/ kg (0.12 (0.125)) 12 hourly IV — Dose depends upon blood sugar level 35 to 70 IU (52 (52.5)) As recommended. SC — In divided doses. Dose depends upon blood sugar level

0.25 to 0.5 IU/kg (0.38 (0.375)) 24 hourly Subcutaneous — -

0.25 to 0.5 IU/kg (0.38 (0.375)) 24 hourly Subcutaneous —

Many drugs can affect your blood sugar and may also affect insulin glargine. This includes prescription and over-the-counter medicines, vitamins, and herbal products . Tell your doctor about all other medicines you use. Not all possible interactions are listed here. Tell your doctor if you also take pioglitazone or rosiglitazone (sometimes contained in combinations with glimepiride or metformin). Taking certain oral diabetes medicines while you are using insulin may increase your risk of serious heart problems.

Inj Store at room temperature, Below 15°C or in refrigerator. Do not Freeze. Protect from Sunlight. Use within 2 years(at 4C) if refrigerated and within 1 month if kept at room temperature.