Medicines/Generics/Hydrocortisone

Hydrocortisone

Generic medicine reference

Not yet clinically reviewed

This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.

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Overview

Hydrocortisone butyrate (Locoid Lipocream, Locoid Lotion) is used to help skin conditions that respond to steroid creams. Locoid lotion can be used for mild to moderate atopic dermatitis in patients 3 years and older. Locoid Lipocream can be used for mild to moderate atopic dermatitis in pediatric patients 3 months to 18 years of age, and also for inflamed and itchy skin conditions that respond to steroid creams. Hydrocortisone butyrate lotion and lipocream is a corticosteroid (cortisone-like medicine or steroid). Hydrocortisone butyrate is only available on prescription.

Indications

Contraindications

Hydrocortisone is contraindicated in conditions like Ulcers, Untreated serious infections, Hypersensitivity, Idiopathic thrombocytopenic purpura, Premature infants, Systemic fungal infections.

Side Effects

The most common hydrocortisone butyrate side effects are application site reactions, which occur in more than 1% of patients Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Also, see the warnings section.

Warnings

Endocrine System Adverse Reactions: Reversible hypothalamic-pituitary-adrenal (HPA) axis suppression may occur, with the potential for glucocorticosteroid insufficiency. Consider periodic evaluations for HPA axis suppression if LOCOID Lotion is applied to large surface areas or used under occlusion. If HPA axis suppression is noted, reduce the application frequency, discontinue use, or switch to a lower potency corticosteroid. Systemic effects of topical corticosteroids may also include manifestations of Cushing’s syndrome, hyperglycemia, and glucosuria. Pediatric patients may be more susceptible to systemic toxicity due to their larger skin-surface-to-body-mass ratios. Ophthalmic Adverse Reactions: Topical corticosteroids, including Locoid, may increase the risk of cataracts and glaucoma. If visual symptoms occur, consider referral to an ophthalmologist. Skin Infections: Initiate appropriate therapy if skin infections develop in the treated area. ( 5.3 )

High Risk Groups

Adult Dosage

0.1 to 2 % (1 (1.05)) 8 hourly Topical — As Required 1 % (1 (1)) As recommended. Ophthalmic — As Required 100 to 500 mg (300 (300)) 8 hourly IV —

Child Dosage

1 % (1 (1)) As recommended. Opthalmic — As Required 5 mg/kg (5 (5)) 6 hourly Intra Muscular — - 5 mg/kg (5 (5)) 6 hourly Intra Venous — -

Neonatal Dosage

6.25 mg/kg (6.2 (6.25)) 6 hourly Intramuscular — 6.25 mg/kg (6.2 (6.25)) 6 hourly Intravenous —

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Storage

Inj, Oral Susp, Dental Paste, Cream, Oint Store Below 40°C. Do not Freeze. Protect from Sunlight. Suppositories Store at room temperature, Below 15°C or in refrigerator. Do not Freeze. Protect from Sunlight and Moisture. Tab Store at room temperature.

Available Brands in Pakistan

32 active brands listed alphabetically.

Hydrocortisone

Available Brands in Pakistan

BIO-CORT

CLOZOLE-H

CORTICORT

CORTIDERM

CORTISEL

CORTIVAL

CUTIS-HC

DAKTACORT

DAKTACORTCREAM

DERMICON HC

DIPCORT

FURTIGENT

GEM-COT

GEN-COT

GENTICYN-HC

HY-CORTISONE

HYDROCORTISONE

HYDROCORTISONE

HYDROCORTISONE

HYDRO SOD SUC

HYDROVATE

HYZONATE

MYCON-H

MYCONIT-H

NEO CORT

OTOGEN-HC

OTOSPORIN

POSTERISAN FORTE

SOLU CORTEF

SOLU-HYDROCORT

SOLUTINA

ZIPO