Medicines/Generics/Hyoscine (Butylbromide)

Hyoscine (Butylbromide)

Generic medicine reference

Not yet clinically reviewed

This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.

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Overview

Hyoscine (Butylbromide) used as an antispasmodic agent. Hyoscine (Butylbromide) also used as an antiemetic for travel sickness.

Indications

Hyoscine (Butylbromide) is primarily indicated in conditions like Acute spasm and spasm in diagnostic procedures, Aspiration prophylaxis, Bradycardia, Cycloplegia induction, Drying secretions, amnesia, Iritis, Irritable bowel syndrome, Motion sickness, Mydriasis induction, Reduction of excessive respiratory secretions (death rattle) in palliative care, Smooth muscle spasm, Symptomatic relief of GI-disorders, The pain of bowel colic in palliative care, Uveitis, and can also be given in adjunctive therapy as an alternative drug of choice in Premedication in anaesthesia.

Contraindications

Hyoscine (Butylbromide) is contraindicated in conditions like Glaucoma, Prostatic hypertrophy, Paralytic ileus.

Side Effects

Hyoscine (Butylbromide) produces potentially life-threatening effects which include Seizures, Hallucination, Transient arrhythmias. which are responsible for the discontinuation of Hyoscine (Butylbromide) therapy. The signs and symptoms that are produced after the acute overdosage of Hyoscine (Butylbromide) include Coma, Blurred vision, Hallucinations, Dry flushed skin, Delirium, Ataxia, Restlessness, Rapid & irregular pulse, Decreased salivary secretions, Increased heart rate, Loss of accommodation, Flushed skin, scarlet, weak pulse, Excitement. The symptomatic adverse reactions produced by Hyoscine (Butylbromide) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Thirst, Headache, Drowsiness, Fatigue, Restlessness, Palpitation, Tachycardia, Constipation, Dry mouth, Nausea and vomiting, Blurring of vision, Mydriasis, Loss of accommodation, Transient bradycardia, Delirium, Swallowing difficulties, Urinary Retention, Cycloplegia.

Warnings

Hyoscine butyl bromide should be used with caution in patients with any allergy (especially drug allergies), glaucoma (narrow-angle), liver or kidney disease or severe narrowing of the stomach, intestines or bladder. Limit alcohol intake, as it may worsen certain side effects of this medication. Since this drug may cause dizziness, drowsiness and blurred vision, so use with caution while driving or performing tasks requiring alertness. Protect eyes from bright light and wear UVA/UVB sunglasses while eyes are dilated. It should be used only when clearly needed during pregnancy. The elderly and children are particularly sensitive to the side effects of this drug, therefore caution is advised with use of this drug. Should be use with caution in GERD, Ulcerative colitis, Close angle glaucoma to pyrexia.

High Risk Groups

Drug should not be given to Paediatrics, Pregnant Mothers, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Adult Dosage

0.4 mg (0.4 (0.4)) 4 hourly PO — for GI & Genitourinary conditions 10 to 0 mg (5 (5)) 4 hourly PO — In Anti spasmodic condition 5 to 0 mg/hr (2.5 (2.5)) As recommended. Slow IV —

Child Dosage

10 to 20 ug/kg (15 (15)) As recommended. Intra Muscular — Single Dose 10 to 20 ug/kg (15 (15)) As recommended. Subcutaneous — Single Dose

Neonatal Dosage

No neonatal dosage information is recorded for this medicine yet.

Drug Interactions

Hyoscine (Butylbromide) is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAlcoholBarium SulphateEphedrine These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Storage

Inj Store Below 30°C. Do not Freeze. Tab Store in a well closed container, Below 30°C. Protect from Sunlight.

Available Brands in Pakistan

26 active brands listed alphabetically.

Hyoscine (Butylbromide)

Available Brands in Pakistan

BUSCOPAN

BUSCOPAN COMPOUND

BUSCOPHARM

DEENOPAN

FLOPAN

HYMEX

HYOMIDE

HYOPEN

HYOPEN PLAIN

HYO-PLUS

HYOSCINE

HYOSCINE

HYOSCINE

HYOSCINE

HYOSCINE

HYOSCINE COMPOUND

HYOSCINE COMPOUND

HYOSCINE COMPOUND

HYOSCINE COMPOUND

HYOSCINE COMPOUND

HYOSCINE COMPOUND

HYOSCINE COMPOUND

HYOSCINE COMPOUND

HYOSCINE COMPOUND

HYSOPAN

SPASLER-P