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Medicines/Generics/Hyoscine (Butylbromide)

Hyoscine (Butylbromide)

Generic medicine reference

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Overview
Hyoscine (Butylbromide) used as an antispasmodic agent. Hyoscine (Butylbromide) also used as an antiemetic for travel sickness.
Indications
Hyoscine (Butylbromide) is primarily indicated in conditions like Acute spasm and spasm in diagnostic procedures, Aspiration prophylaxis, Bradycardia, Cycloplegia induction, Drying secretions, amnesia, Iritis, Irritable bowel syndrome, Motion sickness, Mydriasis induction, Reduction of excessive respiratory secretions (death rattle) in palliative care, Smooth muscle spasm, Symptomatic relief of GI-disorders, The pain of bowel colic in palliative care, Uveitis, and can also be given in adjunctive therapy as an alternative drug of choice in Premedication in anaesthesia.
Contraindications
Hyoscine (Butylbromide) is contraindicated in conditions like Glaucoma, Prostatic hypertrophy, Paralytic ileus.
Side Effects
Hyoscine (Butylbromide) produces potentially life-threatening effects which include Seizures, Hallucination, Transient arrhythmias. which are responsible for the discontinuation of Hyoscine (Butylbromide) therapy. The signs and symptoms that are produced after the acute overdosage of Hyoscine (Butylbromide) include Coma, Blurred vision, Hallucinations, Dry flushed skin, Delirium, Ataxia, Restlessness, Rapid & irregular pulse, Decreased salivary secretions, Increased heart rate, Loss of accommodation, Flushed skin, scarlet, weak pulse, Excitement. The symptomatic adverse reactions produced by Hyoscine (Butylbromide) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Thirst, Headache, Drowsiness, Fatigue, Restlessness, Palpitation, Tachycardia, Constipation, Dry mouth, Nausea and vomiting, Blurring of vision, Mydriasis, Loss of accommodation, Transient bradycardia, Delirium, Swallowing difficulties, Urinary Retention, Cycloplegia.
Warnings
Hyoscine butyl bromide should be used with caution in patients with any allergy (especially drug allergies), glaucoma (narrow-angle), liver or kidney disease or severe narrowing of the stomach, intestines or bladder. Limit alcohol intake, as it may worsen certain side effects of this medication. Since this drug may cause dizziness, drowsiness and blurred vision, so use with caution while driving or performing tasks requiring alertness. Protect eyes from bright light and wear UVA/UVB sunglasses while eyes are dilated. It should be used only when clearly needed during pregnancy. The elderly and children are particularly sensitive to the side effects of this drug, therefore caution is advised with use of this drug. Should be use with caution in GERD, Ulcerative colitis, Close angle glaucoma to pyrexia.
High Risk Groups
Drug should not be given to Paediatrics, Pregnant Mothers, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
0.4 mg (0.4 (0.4)) 4 hourly PO — for GI & Genitourinary conditions 10 to 0 mg (5 (5)) 4 hourly PO — In Anti spasmodic condition 5 to 0 mg/hr (2.5 (2.5)) As recommended. Slow IV —
Child Dosage
10 to 20 ug/kg (15 (15)) As recommended. Intra Muscular — Single Dose 10 to 20 ug/kg (15 (15)) As recommended. Subcutaneous — Single Dose
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Hyoscine (Butylbromide) is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAlcoholBarium SulphateEphedrine These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Storage
Inj Store Below 30°C. Do not Freeze. Tab Store in a well closed container, Below 30°C. Protect from Sunlight.

Available Brands in Pakistan

26 active brands listed alphabetically.

BUSCOPAN

Active

MARTIN DOW PHARMACEUTICALS (PAK) LTD.

DML: BUSCOPAN

InjTabs

BUSCOPAN COMPOUND

Active

MARTIN DOW PHARMACEUTICALS (PAK) LTD.

DML: BUSCOPAN COMPOUND

Comp InjComp Tabs

BUSCOPHARM

Active

EPHARM LABORATORIES

DML: BUSCOPHARM

Inj

DEENOPAN

Active

DELUX CHEMICAL INDUSTRIES

DML: DEENOPAN

Tabs

FLOPAN

Active

FLOW PHARMACEUTICALS (PVT) LTD.

DML: FLOPAN

Tabs

HYMEX

Active

ELITE PHARMA

DML: HYMEX

Inj

HYOMIDE

Active

PARAMOUNT PHARMACEUTICALS

DML: HYOMIDE

Syrup

HYOPEN

Active

MASS PHARMA (PRIVATE) LIMITED

DML: HYOPEN

Inj

HYOPEN PLAIN

Active

HARMANN PHARMACEUTICAL LABORATORIES (PVT) LTD.

DML: HYOPEN PLAIN

Inj

HYO-PLUS

Active

RORYAN PHARMACEUTICAL INDUSTRIES (PVT) LTD

DML: HYO-PLUS

Tabs

HYOSCINE

Active

VENUS PHARMA

DML: HYOSCINE

Inj

HYOSCINE

Active

MUNAWAR PHARMA (PVT) LTD.

DML: HYOSCINE

Tabs

HYOSCINE

Active

AMROS PHARMACEUTICALS.

DML: HYOSCINE

Inj

HYOSCINE

Active

HEALERS LABORATORIES

DML: HYOSCINE

Tabs

HYOSCINE

Active

SEMOS PHARMACEUTICALS (PVT) LTD.

DML: HYOSCINE

Tabs

HYOSCINE COMPOUND

Active

UNIPHARMA (PVT) LTD.

DML: HYOSCINE COMPOUND

Tabs

HYOSCINE COMPOUND

Active

MEDICAIDS PAKISTAN (PVT) LTD.

DML: HYOSCINE COMPOUND

Tabs

HYOSCINE COMPOUND

Active

WILSHIRE LABORATORIES (PVT) LTD.

DML: HYOSCINE COMPOUND

Tabs

HYOSCINE COMPOUND

Active

AMROS PHARMACEUTICALS.

DML: HYOSCINE COMPOUND

Inj

HYOSCINE COMPOUND

Active

VENUS PHARMA

DML: HYOSCINE COMPOUND

Inj

HYOSCINE COMPOUND

Active

MUNAWAR PHARMA (PVT) LTD.

DML: HYOSCINE COMPOUND

Inj

HYOSCINE COMPOUND

Active

EFROZE CHEMICAL INDUSTRIES (PVT) LTD.

DML: HYOSCINE COMPOUND

Tabs

HYOSCINE COMPOUND

Active

AL-SHIFA PHARMACEUTICALS

DML: HYOSCINE COMPOUND

Inj

HYOSCINE COMPOUND

Active

UNEXO LABS (PVT) LTD.

DML: HYOSCINE COMPOUND

Tabs

HYSOPAN

Active

MEDICAIDS PAKISTAN (PVT) LTD.

DML: HYSOPAN

InjTabs

SPASLER-P

Active

AGP (PRIVATE) LTD.

DML: SPASLER-P

Syrup

For educational purposes only. Check current guidelines and consult a qualified healthcare professional before making clinical decisions.