Pharmapedia Pro
Medicines/Generics/Hyoscyamine

Hyoscyamine

Generic medicine reference

Not yet clinically reviewed

This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.

Spot an error in this entry? Submit a correction
Overview
Hyoscyamine is used to treat many different stomach and intestinal disorders, including peptic ulcer and irritable bowel syndrome . It is also used to control muscle spasms in the bladder, kidneys, or digestive tract, and to reduce stomach acid. Hyoscyamine is sometimes used to reduce tremors and rigid muscles in people with symptoms of Parkinson's disease . Hyoscyamine is also used as a drying agent to control excessive salivation , runny nose, or excessive sweating. Hyoscyamine may also be used for purposes not listed in this medication guide.
Indications
Hyoscyamine is used to treat many different stomach and intestinal disorders, including peptic ulcer and irritable bowel syndrome . It is also used to control muscle spasms in the bladder, kidneys, or digestive tract, and to reduce stomach acid. Hyoscyamine is sometimes used to reduce tremors and rigid muscles in people with symptoms of Parkinson's disease . Hyoscyamine is also used as a drying agent to control excessive salivation , runny nose, or excessive sweating. Hyoscyamine may also be used for purposes not listed in this medication guide.
Contraindications
You should not use hyoscyamine if you are allergic to it, or if you have: a bladder obstruction or other urination problems; an enlarged prostate ; a stomach or bowel obstruction (including paralytic ileus ); severe ulcerative colitis, or toxic megacolon; glaucoma; or myasthenia gravis. Hyoscyamine is not approved for use by anyone younger than 2 years old. Tell your doctor if you have ever had: heart problems; high blood pressure ; kidney disease; a colostomy or ileostomy; a thyroid disorder; or hiatal hernia with GERD (gastroesophageal reflux disease). It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.
Side Effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Hyoscyamine may cause serious side effects. Stop using hyoscyamine and call your doctor at once if you have: anxiety, confusion, hallucinations, unusual thoughts or behavior; weakness, memory problems; slurred speech; problems with balance or muscle movement; diarrhea; o pounding heartbeats or fluttering in your chest. Common side effects of hyoscyamine may include: dizziness, drowsiness, feeling weak or tired; decreased sweating, decreased urination; blurred vision; rash; dry mouth, decreased sense of taste; stomach pain, nausea, vomiting, bloating; diarrhea, constipation ; headache; sleep problems (insomnia); or impotence, loss of interest in sex, or trouble having an orgasm. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
You should not use hyoscyamine if you have urination problems, a stomach or bowel obstruction , severe ulcerative colitis , glaucoma, or myasthenia gravis .
High Risk Groups
You should not use hyoscyamine if you have urination problems, a stomach or bowel obstruction , severe ulcerative colitis , glaucoma, or myasthenia gravis .
Adult Dosage
150 to 250 ug (200 (200)) 6 hourly PO,SL — 250 to 500 ug (380 (375)) 6 hourly IV,SC — Scraped Dose — Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Always follow directions on the medicine label about giving hyoscyamine to a child. Swallow an extended-release tablet whole and do not crush, chew, or break it. Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon). Remove an orally disintegrating tablet from the package only when you are ready to take the medicine. Place the tablet on your tongue and allow it to dissolve. Swallow several times as the tablet dissolves. You may drink water after the pill has completely dissolved. Store at room temperature away from moisture and heat.
Child Dosage
0.75 mg/kg (0.75 (0.75)) As recommended. — 2.08 to 8.33 ug/kg (5.2 (5.205)) 6 hourly Oral — Recommended for Paeds of 2-12 years of age
Neonatal Dosage
4.6 ug/kg (4.6 (4.6)) 6 hourly Oral —
Drug Interactions
Tell your doctor about all your other medicines, especially: an antidepressant; medicine to treat mental illness; cold or allergy medicine (Benadryl and others); medicine to treat or prevent nausea and vomiting; or an MAO inhibitor-- isocarboxazid , linezolid, methylene blue injection, phenelzine , rasagiline , selegiline, tranylcypromine , and others. This list is not complete. Other drugs may affect hyoscyamine, including prescription and over-the-counter medicines, vitamins, and herbal products . Not all possible drug interactions are listed here.
Storage
Tab, Caps, Elixir Store at room temperature, Below 40°C. Protect from Sunlight and Moisture.

Available Brands in Pakistan

2 active brands listed alphabetically.

ANAPAZ

Active

HILTON PHARMA (PVT) LIMITED

DML: ANAPAZ

DropsTabs DS

PAN CALM

Active

IMCO PHARMACEUTICALS LABORATORIES

DML: PAN CALM

Drops

2 additional records are present but flagged "Unverified / Legacy" and not listed.