Indinavir (Sulphate)
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Indinavir is used alone or in combination with other anti-HIV medicines to treat infection caused by the human immunodeficiency virus (HIV). HIV is the virus that causes acquired immune deficiency syndrome (AIDS).
Indinavir will not cure or prevent HIV infection or AIDS. It helps keep HIV from reproducing and appears to slow down the destruction of the immune system. This may help delay problems that are usually related to AIDS or HIV disease from occurring. Indinavir will not keep you from spreading HIV to other people. People who receive this medicine may continue to have other problems usually related to AIDS or HIV disease.
This medicine is available only with your doctor's prescription.
Indications
Indinavir is used alone or in combination with other anti-HIV medicines to treat infection caused by the human immunodeficiency virus (HIV). HIV is the virus that causes acquired immune deficiency syndrome (AIDS).
Indinavir will not cure or prevent HIV infection or AIDS. It helps keep HIV from reproducing and appears to slow down the destruction of the immune system. This may help delay problems that are usually related to AIDS or HIV disease from occurring. Indinavir will not keep you from spreading HIV to other people. People who receive this medicine may continue to have other problems usually related to AIDS or HIV disease.
This medicine is available only with your doctor's prescription.
Contraindications
Indinavir (Sulphate) is contraindicated in conditions like Diabetes mellitus, Hemophilia, Hypersensitivity.
Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
Blood in the urine sharp back pain just below the ribs
Less common
Abdominal or stomach pain chills clay-colored stools dark urine dizziness fever headache itching loss of appetite nausea rash unpleasant breath odor unusual tiredness or weakness vomiting of blood yellow eyes or skin
Rare
Confusion dehydration dry or itchy skin fruity mouth odor increased hunger increased thirst increased urination pale skin troubled breathing with exertion unusual bleeding or bruising unusual tiredness or weakness vomiting weight loss
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Change in sense of taste diarrhea difficulty with sleeping generalized weakness
Less common
Acid or sour stomach acid regurgitation belching cough general feeling of discomfort or illness heartburn increase in appetite indigestion sleepiness
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Warnings
Caution is required in diabetic patient, patients with hemophilia who may experienced increased bleeding. Indinavir should be used with caution and possible dose reduction is needed in hepatic impairment. Adequate hydration is recommended to avoid any risk of nephrolithiasis. Monitoring is required in case of renal impairment. Avoid in porphyrid hepatic impairment , Preexisting livered disease or chronic hepatitis B&C treatment may need to be stopped or temperature interrupted in patient developing nephrolithiasis caution in a eating patient with hemophilis A&B as report of spontaneous Bleeding with use of HIV use of the HIV protease inhibitor
High Risk Groups
Drug should not be given to Paediatrics, Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
800 mg (800 (800)) 8 hourly PO —
Child Dosage
500 mg/m2 (500 (500)) 8 hourly PO — child under 4 year safety not establish
800 mg/m2 (800 (800)) 8 hourly PO — Child 4-7 year,
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Alfuzosin Alprazolam Amiodarone Astemizole Atazanavir Cisapride Colchicine Conivaptan Dihydroergotamine Dronedarone Eletriptan Eliglustat Eplerenone Ergoloid Mesylates Ergonovine Ergotamine Finerenone Flibanserin Gepirone Isavuconazonium Sulfate Ivabradine Levoketoconazole Lomitapide Lovastatin Lurasidone Maraviroc Mavacamten Methylergonovine Midazolam Naloxegol Nimodipine Pacritinib Pimozide Ranolazine Sildenafil Silodosin Simvastatin Terfenadine Tolvaptan Triazolam Ubrogepant Venetoclax Voclosporin
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Acalabrutinib Adagrasib Ado-Trastuzumab Emtansine Alfentanil Apalutamide Aprepitant Aripiprazole Artemether Atogepant Atorvastatin Avacopan Avanafil Avapritinib Axitinib Bedaquiline Belzutifan Benzhydrocodone Boceprevir Bosutinib Brentuximab Vedotin Brexpiprazole Brigatinib Bromocriptine Budesonide Buprenorphine Cabazitaxel Cabotegravir Cabozantinib Calcifediol Carbamazepine Cariprazine Ceritinib Cerivastatin Cilostazol Clozapine Cobimetinib Codeine Copanlisib Crizotinib Cyclophosphamide Dabrafenib Daclatasvir Daridorexant Darunavir Dasatinib Deflazacort Delamanid Dexamethasone Dihydrocodeine Domperidone Doxorubicin Doxorubicin Hydrochloride Liposome Drospirenone Duvelisib Elacestrant Elagolix Elexacaftor Encorafenib Entrectinib Enzalutamide Erlotinib Eszopiclone Ethinyl Estradiol Etravirine Everolimus Fedratinib Fentanyl Fesoterodine Fexinidazole Fluconazole Fluticasone Fosaprepitant Fosnetupitant Garlic Gilteritinib Glasdegib Hydrocodone Ibrexafungerp Ibrutinib Idelalisib Ifosfamide Iloperidone Infigratinib Irinotecan Irinotecan Liposome Istradefylline Ivacaftor Ivosidenib Ixabepilone Ketoconazole Lapatinib Larotrectinib Lefamulin Lemborexant Lenacapavir Leniolisib Levomilnacipran Lorlatinib Lumacaftor Lumateperone Lurbinectedin Macitentan Manidipine Meperidine Methadone Midostaurin Mifepristone Mirtazapine Mirvetuximab Soravtansine-gynx Mitapivat Mobocertinib Neratinib Netupitant Nilotinib Norethindrone Norgestimate Olaparib Olutasidenib Omaveloxolone Omeprazole Orlistat Osilodrostat Oxycodone Palbociclib Palovarotene Panobinostat Pazopanib Pemigatinib Pentazocine Pexidartinib Phenobarbital Pimavanserin Piperaquine Pirtobrutinib Ponatinib Pralsetinib Primidone Quetiapine Quizartinib Reboxetine Regorafenib Retapamulin Ribociclib Rifabutin Rifampin Rifapentine Rimegepant Ritlecitinib Rivaroxaban Romidepsin Rosuvastatin Ruxolitinib Salmeterol Saquinavir Selpercatinib Selumetinib Simeprevir Sirolimus Protein-Bound Sonidegib Sparsentan St John's Wort Sufentanil Sunitinib Suvorexant Tacrolimus Tadalafil Tamsulosin Tazemetostat Temsirolimus Tezacaftor Thiotepa Ticagrelor Tipranavir Tocilizumab Toremifene Trabectedin Tramadol Trazodone Trofinetide Upadacitinib Valbenazine Vamorolone Vardenafil Vemurafenib Vilanterol Vilazodone Vinblastine Vincristine Vincristine Sulfate Liposome Vinflunine Vorapaxar Zanubrutinib Zolpidem Zuranolone
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Amlodipine Amprenavir Aripiprazole Lauroxil Ascorbic Acid Clarithromycin Clevidipine Cobicistat Cyclosporine Dalfopristin Delavirdine Didanosine Diltiazem Efavirenz Felodipine Isradipine Itraconazole Levodopa Nevirapine Nicardipine Nifedipine Nisoldipine Quinupristin Ritonavir Verapamil
Storage
Caps Store at room temperature, Between 15°C-30°C. Protect from Moisture.
Available Brands in Pakistan
No brands are recorded for this generic.
