Insulin Lispro
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Insulin Lispro is a hormone that works by lowering levels of glucose (sugar) in the blood. Insulin lispro is a fast-acting insulin that starts to work about 15 minutes after injection, peaks in about 1 hour, and keeps working for 2 to 4 hours.
Insulin lispro is used to improve blood sugar control in adults and children with diabetes mellitus .
Admelog and HumaLOG are used to treat type 2 diabetes in adults, or type 1 diabetes in adults and children who are at least 3 years old.
Lyumjev is not approved for use by anyone younger than 18 years old.
Indications
Insulin Lispro is a hormone that works by lowering levels of glucose (sugar) in the blood. Insulin lispro is a fast-acting insulin that starts to work about 15 minutes after injection, peaks in about 1 hour, and keeps working for 2 to 4 hours.
Insulin lispro is used to improve blood sugar control in adults and children with diabetes mellitus .
Admelog and HumaLOG are used to treat type 2 diabetes in adults, or type 1 diabetes in adults and children who are at least 3 years old.
Lyumjev is not approved for use by anyone younger than 18 years old.
Contraindications
You should not use insulin lispro if you are allergic to it, or if you are having an episode of hypoglycemia ( low blood sugar ).
Insulin lispro should not be given to a child younger than 3 years old. Insulin lispro should not be used to treat type 2 diabetes in a child of any age.
To make sure Insulin lispro is safe for you, tell your doctor if you have ever had:
liver or kidney disease; heart problems; or low levels of potassium in your blood ( hypokalemia ).
Tell your doctor if you also take medicine that contains pioglitazone or rosiglitazone . Taking certain oral diabetes medicines while you are using insulin lispro may increase your risk of serious heart problems.
Tell your doctor if you are pregnant or breastfeeding.
Follow your doctor's instructions about using insulin lispro if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby.
Side Effects
Get emergency medical help if you have signs of insulin allergy: redness or swelling where an injection was given, itchy skin rash over the entire body, trouble breathing, fast heartbeats, feeling like you might pass out, or swelling in your tongue or throat.
Call your doctor at once if you have:
weight gain, swelling in your hands or feet, feeling short of breath; low blood sugar - headache , hunger, sweating, irritability, dizziness , fast heart rate , and feeling anxious or shaky; or low potassium - leg cramps, constipation , irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling.
Common Insulin lispro side effects may include:
low blood sugar; weight gain; swelling in your hands or feet; itching; or thickening or hollowing of the skin where you injected the medicine.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
Do not share your Insulin lispro with another person. This includes any pens, cartridge devices, needles, or syringes, even if the needle has been changed. Sharing may pass infections from one person to another. This includes infections you may not know you have.
Low blood sugar may happen with insulin lispro. Very low blood sugar can lead to seizures, passing out, long lasting brain damage, and sometimes death.
Low blood potassium may also happen with insulin lispro. If not treated, this can lead to a heartbeat that is not normal, very bad breathing problems, and sometimes death.
It may be harder to control blood sugar during times of stress such as fever, infection, injury, or surgery. A change in physical activity, exercise, or diet may also affect blood sugar.
Do not drive if your blood sugar has been low. There is a greater chance of you having a crash.
Talk with your doctor before you drink alcohol or take products that have alcohol in them.
High Risk Groups
Do not share your Insulin lispro with another person. This includes any pens, cartridge devices, needles, or syringes, even if the needle has been changed. Sharing may pass infections from one person to another. This includes infections you may not know you have.
Low blood sugar may happen with insulin lispro. Very low blood sugar can lead to seizures, passing out, long lasting brain damage, and sometimes death.
Low blood potassium may also happen with insulin lispro. If not treated, this can lead to a heartbeat that is not normal, very bad breathing problems, and sometimes death.
It may be harder to control blood sugar during times of stress such as fever, infection, injury, or surgery. A change in physical activity, exercise, or diet may also affect blood sugar.
Do not drive if your blood sugar has been low. There is a greater chance of you having a crash.
Talk with your doctor before you drink alcohol or take products that have alcohol in them.
Adult Dosage
0.5 to 1.2 units/kg/day (0.85 (0.85)) As recommended. SC — The dosage of insulin lispro must be individualized. Blood glucose monitoring is essential in all patients receiving insulin
therapy.
It may be administered by continuous subcutaneous infusion by an external insulin pump. Do not use diluted or mixed insulins in external insulin pumps. Infusion sites should be rotated within the same region to reduce the risk of lipodystrophy . Change insulin lispro in the reservoir at least every 7 days, change the infusion sets and the infusion set insertion site at least every 3 days.
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Many other medicines can affect your blood sugar, and some medicines can increase or decrease the effects of insulin. Some drugs can also cause you to have fewer symptoms of hypoglycemia, making it harder to tell when your blood sugar is low. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using. This includes prescription and over-the-counter medicines, vitamins , and herbal products .
Storage
No storage information is recorded for this medicine yet.
