Insulin Lispro Protamine
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Insulin lispro protamine suspension (NPL component) is a suspension of crystals produced from combining insulin lispro and protamine sulfate under appropriate conditions for crystal formation. This medication is used to control blood sugar in patients with diabetes mellitus. Controlling high blood sugar helps prevent heart disease, strokes, kidney disease, blindness and circulation problems. It promotes glucose transport, which stimulates carbohydrate metabolism in skeletal and cardiac muscle and adipose tissue. Also promotes phosphorylation of glucose in liver, where it's converted to glycogen. Directly affects fat and protein metabolism, stimulates protein synthesis, inhibits release of free fatty acids, and indirectly decreases phosphate and potassium. It is available in premixed form with insulin lispro in 75/25 and 50/50 ratio.
Indications
Insulin Lispro Protamine is primarily indicated in conditions like Type I diabetes mellitus, Type II diabetes mellitus.
Contraindications
Insulin Lispro Protamine
Side Effects
The symptomatic adverse reactions produced by Insulin Lispro Protamine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Chills, Tingling of the hand, Hypoglycemia, Fainting.
Warnings
its doses will vary among patients and should be determined by the healthcare provider familiar with the patient’s metabolic needs, eating habits, and other lifestyle variablesThe dose of insulin lispro protamine when available in combination with insulin lispro (75/25 or 50/50 ratio) should be given within 15 minutes before a meal.
High Risk Groups
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
Sc ( ) —
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
No data regarding the interactions of Insulin Lispro Protamine was found.
Storage
Store in a well closed container, Below 25°C. Refrigeration and Freezing is not recommended.
Available Brands in Pakistan
No brands are recorded for this generic.