Iron Sorbitol

Tafamidis (brand names Vyndaqel and Vyndamax) is a transthyretin stabilizer that may be given to reduce death or hospitalization caused by heart problems in adults with cardiomyopathy (damage of the heart muscle) caused by wild-type or hereditary transthyretin-mediated amyloidosis (ATTR-CM). Tafamidis works by attaching to the transthyretin protein, an important protein primarily produced by the liver, but also in small amounts by the outer lining of the brain and retina. TTR carries the thyroid hormone thyroxine and retinol (vitamin A) throughout the body. Tafamidis stabilizes TTR, helping it to stay together, and slowing the breakdown and build-up of dangerous deposits, which can help slow the progression of ATTR-CM. Tafamidis is available as Vyndaqel (tafamidis meglumine) and Vyndamax (tafamidis) which were both FDA approved on May 3, 2019. There is no generic Vyndaqel or Vyndamax.

Tafamidis (brand names Vyndaqel and Vyndamax) is a transthyretin stabilizer that may be given to reduce death or hospitalization caused by heart problems in adults with cardiomyopathy (damage of the heart muscle) caused by wild-type or hereditary transthyretin-mediated amyloidosis (ATTR-CM). Tafamidis works by attaching to the transthyretin protein, an important protein primarily produced by the liver, but also in small amounts by the outer lining of the brain and retina. TTR carries the thyroid hormone thyroxine and retinol (vitamin A) throughout the body. Tafamidis stabilizes TTR, helping it to stay together, and slowing the breakdown and build-up of dangerous deposits, which can help slow the progression of ATTR-CM. Tafamidis is available as Vyndaqel (tafamidis meglumine) and Vyndamax (tafamidis) which were both FDA approved on May 3, 2019. There is no generic Vyndaqel or Vyndamax.

Before taking tafamidis, tell your healthcare provider about all your medical conditions, including if you: have liver problems are pregnant or plan to become pregnant are breastfeeding or plan to breastfeed.

There are no common side effects reported for tafamidis , but diarrhea has been reported as a possible side effect post-approval. People taking tafamidis do not require any additional lab testing or monitoring. As with any medicine, hypersensitivity (allergic) reactions are possible. Get emergency medical help if you have signs of an allergic reaction, such as hives; difficulty breathing; or swelling of your face, lips, tongue, or throat. There are no warnings, contraindications, or serious side effects listed for tafamidis. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Iron sorbitol should be administered only by IM injection in the treatment of accurately diagnosed iron deficiency anemia

Drug should not be given to Pregnant Mothers. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

2 ml (2 (2)) As recommended. IM — This two mL iron sorbitol contains the recommended single daily dose (100 mg) for an adult of 70 kg body weight.

( ) — Not recommended in this age group

No neonatal dosage information is recorded for this medicine yet.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Some medicines may affect the way tafamidis works, and tafamidis may affect how some medicines work. Especially tell your healthcare provider if you take: medications that are BCRP substrates such as methotrexate, rosuvastatin, or imatinib. Your healthcare provider may need to reduce the dosage of these medications. Know the medicines you take. Keep a list of all your medicines. Show them to your healthcare provider or pharmacist when you get a new medicine. Do not take any new medicine without talking with your doctor.

No storage information is recorded for this medicine yet.