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Medicines/Generics/Isoflurane

Isoflurane

Generic medicine reference

Not yet clinically reviewed

This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.

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Overview
It is used to put you to sleep for surgery . It is used to cause sleep during a procedure.
Indications
It is used to put you to sleep for surgery . It is used to cause sleep during a procedure.
Contraindications
Isoflurane is contraindicated in conditions like Coronary artery disease, Genetic Susceptibility to malignant hyperthermia, Neurological procedures.
Side Effects
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: Signs of an allergic reaction, like rash ; hives; itching ; red, swollen, blistered, or peeling skin with or without fever; wheezing ; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Signs of high potassium levels like a heartbeat that does not feel normal; feeling confused; feeling weak, lightheaded, or dizzy; feeling like passing out; numbness or tingling; or shortness of breath . Very bad dizziness or passing out. Trouble breathing, slow breathing, or shallow breathing. A heartbeat that does not feel normal. Muscle stiffness. Change in color of skin to a bluish color like on the lips, nail beds, fingers, or toes. This medicine may cause a very bad and sometimes deadly problem called malignant hyperthermia. Call your doctor right away if you have a fast heartbeat, fast breathing, fever, or spasm or stiffness of the jaw muscles. Very bad and sometimes deadly liver problems have happened with isoflurane. Call your doctor right away if you have signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
Warnings
Avoid isoflurane in patients having susceptibility to malignant hyperthermia. Patients should observed caution while driving or performing other tasks requiring alertness, because may cause drowsiness. Patients with chronic disease such as diabetes or hypertension may require adjustment of their therapy before anaesthesia. Anesthetics should be given with caution in patients with cardiac, respiratory, renal or hepatic impairment. Avoid use during pregnancy. Isoflurane should be used with caution in patients with pheochromocytoma or with raised intracranial pressure. Use of the isoflurane in the patient with myasthenia gravis can cause an increase in the muscular weakness due to the neuromuscular blocking effect of anesthetics. The drug should be used with caution during pregnancy and lactation.
High Risk Groups
Drug should not be given to Pregnant Mothers, Cardiac / Hypertensive Patients, Geriatrics, and Neonates. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
0.2 to 0.5 % (0.35 (0.35)) As recommended. Inhalation — Aa required
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Isoflurane is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAdrenalineAtracurium (Besylate)DoxapramMivacurium (Cl)Nitric OxideNitrous OxidePancuronium (Br)PropofolPropofolIsoflurane can be expected to increase the anesthetic or sedative and cardiorespiratory effects of Propofol Injectable Emulsion.Suxamethonium (Cl)Vecuronium (Br) These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Storage
Inhaler Store in a well closed container, at room temperature, Between 15°C-30°C. Protect from Sunlight and Heat.