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Medicines/Generics/Isophane insulin

Isophane insulin

Generic medicine reference

Not yet clinically reviewed

This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.

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Overview
Insulin is a hormone that works by lowering levels of glucose (sugar) in the blood. Insulin isophane is a intermediate-acting insulin. Insulin regular is an short-acting insulin. This combination insulin starts to work within 10 to 20 minutes after injection, peaks in 2 hours, and keeps working for up to 24 hours. Insulin isophane and insulin regular is a combination medicine used to improve blood sugar control in adults with diabetes mellitus . Insulin isophane and insulin regular may also be used for purposes not listed in this medication guide.
Indications
Insulin is a hormone that works by lowering levels of glucose (sugar) in the blood. Insulin isophane is a intermediate-acting insulin. Insulin regular is an short-acting insulin. This combination insulin starts to work within 10 to 20 minutes after injection, peaks in 2 hours, and keeps working for up to 24 hours. Insulin isophane and insulin regular is a combination medicine used to improve blood sugar control in adults with diabetes mellitus . Insulin isophane and insulin regular may also be used for purposes not listed in this medication guide.
Contraindications
You should not use this medicine if you are allergic to insulin, or if you are having an episode of hypoglycemia (low blood sugar). This medicine is not approved for use by anyone younger than 18 years old. Tell your doctor if you have ever had: congestive heart failure or other heart problems; liver or kidney disease; or low levels of potassium in your blood ( hypokalemia ). Tell your doctor if you also take pioglitazone or rosiglitazone (sometimes contained in combinations with glimepiride or metformin ). Taking certain oral diabetes medicines while you are using insulin may increase your risk of serious heart problems. Tell your doctor if you are pregnant or breastfeeding. Follow your doctor's instructions about using insulin if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby.
Side Effects
Get emergency medical help if you have signs of insulin allergy: redness or swelling where an injection was given, itchy skin rash over the entire body, trouble breathing, chest tightness, feeling like you might pass out, or swelling in your tongue or throat. Insulin isophane and insulin regular may cause serious side effects. Call your doctor at once if you have: fluid retention --weight gain, swelling in your hands or feet, feeling short of breath; or low potassium --leg cramps, constipation , irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling. Common side effects of insulin isophane and insulin regular may include: low blood sugar ; weight gain, swelling in your hands or feet; itching, mild skin rash; or thickening or hollowing of the skin where you injected the medicine. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
You should not use insulin isophane and insulin regular if you are having an episode of low blood sugar. Never share an injection pen or syringe with another person, even if the needle has been changed.
High Risk Groups
You should not use insulin isophane and insulin regular if you are having an episode of low blood sugar. Never share an injection pen or syringe with another person, even if the needle has been changed.
Adult Dosage
0.2 to 0.5 unit/kg/day (0.35 (0.35)) As recommended. SC — For diabetis 1 mellitus: Honeymoon phase 0.5 to 0.8 unit/kg/day (0.65 (0.65)) As recommended. SC — For diabetis 1 mellitus: Initial dose 0.5 to 1.2 unit/kg/day (0.85 (0.85)) As recommended. SC — For diabetis 1 mellitus: Split dose therapy 0.5 to 1.5 unit/kg/day (1 (1)) As recommended. SC — For diabetis mellitus Type 11: Initial dose, monotherapy 0.7 to 2.5 unit/kg/day (1.6 (1.6)) As recommended. SC — For diabetis 1 mellitus: Insulin resistance 2.5 unit/kg (2.5 (2.5)) As recommended. SC — For diabetis mellitus Type 11: Maintenance dose, monotherapy
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
This insulin may not work as well when you use other medicines at the same time. This includes prescription and over-the-counter medicines, vitamins, and herbal products . Some drugs can also cause you to have fewer symptoms of hypoglycemia, making it harder to tell when your blood sugar is low. Not all possible interactions are listed here. Tell your doctor about all medicines you start or stop using.
Storage
No storage information is recorded for this medicine yet.