Isopropamide (I)

Dextromethorphan and bupropion combination is used to treat major depressive disorder (MDD). This medicine is available only with your doctor's prescription.

Dextromethorphan and bupropion combination is used to treat major depressive disorder (MDD). This medicine is available only with your doctor's prescription.

Isopropamide (I) is contraindicated in conditions like Hypersensitivity to any component of product.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: Less common Fear, nervousness Incidence not known Absence of or decrease in body movement attack, assault, force bigger, dilated, or enlarged pupils (black part of the eye) bleeding gums blistering, peeling, or loosening of the skin bloating bloody, black, tarry stools bloody or cloudy urine bluish color blurred vision burning, tingling, numbness or pain in the hands, arms, feet, or legs change in vision changes in patterns and rhythms of speech changes in skin color chest pain or tightness chills cold sweats coma confusion confusion as to time, place, or person cool, pale skin cough cracks in the skin dark urine deafness decrease in frequency of urination decreased urine output depression diarrhea difficult, burning, or painful urination difficulty in passing urine (dribbling) difficulty in swallowing dizziness dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position drowsiness dry mouth extra heartbeats eye pain fainting false or unusual sense of well-being feeling, seeing, or hearing things that are not there feeling that others can hear your thoughts feeling that others are watching you or controlling your behavior fever flushed, dry skin frequent urge to urinate fruit-like breath odor hallucinations headache heartburn holding false beliefs that cannot be changed by fact inability to move the eyes increased blinking or spasms of the eyelid increased hunger increased in sexual ability, desire, drive, or performance increased interest in sexual intercourse increased sensitivity of the eyes to light increased thirst increased urination indigestion irritability itching itching of the vagina or genital area joint or muscle pain large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs lip smacking or puckering loss of appetite loss of bladder control loss of heat from the body loss of vision muscle cramps, spasms, pain, stiffness, tightness, or weakness nausea nerve pain nightmares pain during sexual intercourse pain or burning in the throat pains in the stomach, side, or abdomen, possibly radiating to the back pounding, slow heartbeat pounding in the ears problems with speech or speaking puffing of cheeks rapid or worm-like movements of tongue red, swollen, or scaly skin red irritated eyes red skin lesions, often with a purple center restlessness seizures sensation of pins and needles severe mood or mental changes shakiness slurred speech sore throat sores, ulcers, or white spots on the lips or tongue or inside the mouth stabbing pain sticking out of the tongue stomach cramps, tenderness, pain, or burning sugar in the urine sweating swelling of the breasts or breast soreness in both females and males swelling of the face, ankles, or hands swelling of the foot or leg swollen, painful, or tender lymph glands in the neck, armpit, or groin swollen glands tenderness tenderness, pain, swelling, warmth, skin discoloration, and prominent superficial veins over the affected area thick, white vaginal discharge with no odor or with a mild odor thoughts of killing oneself changes in behavior trouble breathing trouble sleeping trouble speaking twitching, twisting, uncontrolled repetitive movements of the tongue, lips, face, arms, or legs uncontrolled chewing movements uncontrolled twisting movements of the neck, trunk, arms, or legs unexplained weight loss unusual behavior unusual bleeding or bruising unusual excitement, nervousness, or restlessness unusual facial expressions unusual tiredness or weakness upper right abdominal or stomach pain vomiting vomiting of blood or material that looks like coffee grounds watery or bloody diarrhea yellow eyes and skin Get emergency help immediately if any of the following symptoms of overdose occur: Symptoms of overdose Agitation blurred vision coma confusion dark-colored urine decreased awareness or responsiveness diarrhea difficult or trouble breathing dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position fast, pounding, or irregular heartbeat or pulse fever hyperexcitability inability to move the eyes increased blinking or spasms of the eyelid irregular, fast or slow, or shallow breathing loss of consciousness mental depression or anxiety muscle cramps, spasms, pain, stiffness, or tightness nausea nightmares or unusually vivid dreams overactive reflexes pale or blue lips, fingernails, or skin poor coordination seeing, hearing, or feeling things that are not there seizures severe sleepiness shakiness and unsteady walk shivering sticking out of the tongue sweating talking or acting with excitement you cannot control trembling or shaking twitching uncontrolled twisting movements of the neck, trunk, arms, or legs unsteadiness, trembling, or other problems with muscle control or coordination unusual facial expressions unusual tiredness or weakness vomiting Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Increased sweating Less common Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings constipation Incidence not known Feeling of discomfort inflammation of the joints loss or thinning of the hair muscle aches Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Closely monitor patients for therapeutic response and side effects. Isopropamide iodide should not use in high dose because may produce mental depression and mental disturbances. It should be used with caution in patients over 40yrs. because may increase the risk of glaucoma. It should be used with caution in patients with asthma, heart or renal(kidney) diseases. It should be used with caution in infants and small children.

If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

No adult dosage information is recorded for this medicine yet.

No child dosage information is recorded for this medicine yet.

No neonatal dosage information is recorded for this medicine yet.

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Bromopride Clorgyline Eliglustat Furazolidone Iproniazid Isocarboxazid Linezolid Methylene Blue Moclobemide Nialamide Ozanimod Pargyline Phenelzine Procarbazine Rasagiline Safinamide Selegiline Toloxatone Tranylcypromine Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Acetophenazine Aclidinium Acrivastine Acyclovir Adagrasib Alcaftadine Alfentanil Almotriptan Amantadine Ambenonium Amdinocillin Amdinocillin Pivoxil Amiloride Amineptine Aminophylline Amitriptyline Amitriptylinoxide Amoxapine Amphetamine Amphotericin B Ampicillin Anisotropine Antazoline Aripiprazole Astemizole Atomoxetine Atovaquone Atropine Azatadine Azelastine Azlocillin Aztreonam Bacampicillin Baclofen Balofloxacin Belladonna Alkaloids Benperidol Benzhydrocodone Benzphetamine Bepotastine Besifloxacin Betamethasone Bornaprine Brexpiprazole Bromodiphenhydramine Bromperidol Brompheniramine Buclizine Budesonide Bupivacaine Buprenorphine Bupropion Buspirone Busulfan Butorphanol Butriptyline Butylscopolamine Carbamazepine Carbenicillin Carbimazole Carbinoxamine Carvedilol Chlorambucil Chloroquine Chlorotrianisene Chlorpheniramine Chlorphenoxamine Chlorpromazine Chlorprothixene Cimetidine Cimetropium Cinnarizine Ciprofloxacin Citalopram Clemastine Clemizole Clidinium Clobetasone Clomipramine Clopidogrel Clothiapine Clovoxamine Cloxacillin Clozapine Cocaine Codeine Conjugated Estrogens Corticotropin Cortisone Cosyntropin Cyclacillin Cyclizine Cyclobenzaprine Cyclopentolate Cyclosporine Cyproheptadine Dabrafenib Dalfampridine Danazol Darifenacin Deflazacort Delavirdine Demecarium Desipramine Desonide Desvenlafaxine Deutetrabenazine Dexamethasone Dexbrompheniramine Dexchlorpheniramine Dextroamphetamine Dextromethorphan Dibenzepin Dicloxacillin Dicyclomine Dienestrol Diethylstilbestrol Difenoxin Dihydroartemisinin Dihydrocodeine Dimenhydrinate Dimethindene Diphenhydramine Diphenoxylate Diphenylpyraline Distigmine Dixyrazine Dolasetron Donepezil Dopamine Dothiepin Doxepin Doxofylline Doxorubicin Doxorubicin Hydrochloride Liposome Doxylamine Droperidol Duloxetine Ebastine Echothiophate Edrophonium Efavirenz Eletriptan Emedastine Enflurane Enoxacin Epinastine Escitalopram Esterified Estrogens Estradiol Estramustine Estriol Estrone Estropipate Ethinyl Estradiol Ethopropazine Ethylmorphine Etomidate Famotidine Fedratinib Femoxetine Fenfluramine Fentanyl Fesoterodine Fexinidazole Flavoxate Flecainide Floxacillin Fludrocortisone Flumequine Flunarizine Flunisolide Fluoxetine Fluphenazine Fluticasone Fluvoxamine Foscarnet Fosphenytoin Frovatriptan Galantamine Ganciclovir Gatifloxacin Gepirone Givosiran Glycopyrrolate Granisetron Guanidine Halofantrine Haloperidol Hetacillin Homatropine Hydrocodone Hydrocortisone Hydromorphone Hydroxyamphetamine Hydroxychloroquine Hydroxytryptophan Hydroxyzine Hyoscyamine Ifosfamide Imipenem Imipramine Indalpine Iobenguane I 123 Iobenguane I 131 Iprindole Isoflurane Isoflurophate Isoniazid Isopropamide Ketamine Ketobemidone Ketotifen Lasmiditan Lemborexant Levocabastine Levodopa Levofloxacin Levomilnacipran Levorphanol Lidocaine Lindane Linezolid Lisdexamfetamine Lithium Lofepramine Lomefloxacin Lopinavir Lorcaserin Loxapine Maprotiline Mebeverine Mebhydrolin Meclizine Mefenamic Acid Mefloquine Melitracen Melperone Memantine Mepenzolate Meperidine Meropenem Mesoridazine Mestranol Metaxalone Metformin Methadone Methamphetamine Methantheline Methdilazine Methenolone Methicillin Methimazole Methixene Methotrimeprazine Methylene Blue Methylphenidate Methylprednisolone Methyltestosterone Metoclopramide Metopimazine Metronidazole Mexiletine Mezlocillin Midostaurin Milnacipran Mirtazapine Mizolastine Morphine Morphine Sulfate Liposome Moxifloxacin Nadifloxacin Nafcillin Nalbuphine Nalidixic Acid Nandrolone Naratriptan Nebivolol Nefazodone Neostigmine Nevirapine Niaprazine Nicomorphine Norfloxacin Nortriptyline Ofloxacin Olanzapine Olopatadine Ondansetron Opipramol Opium Opium Alkaloids Oxacillin Oxaliplatin Oxandrolone Oxatomide Oxybutynin Oxycodone Oxymetholone Oxymorphone Palonosetron Panobinostat Papaveretum Paramethasone Paregoric Paroxetine Pazufloxacin Pefloxacin Penicillin G Penicillin V Pentazocine Perazine Periciazine Perphenazine Phenindamine Pheniramine Phenobarbital Phenylpropanolamine Phenyltoloxamine Phenytoin Physostigmine Pimozide Pinaverium Pindolol Pipamperone Piperacillin Piperaquine Pipotiazine Pirenzepine Piritramide Pitolisant Pivampicillin Pizotyline Polyestradiol Phosphate Prednisolone Prednisone Procainamide Procaine Prochlorperazine Proguanil Promazine Promestriene Promethazine Propafenone Propantheline Propicillin Propiverine Propizepine Propofol Propoxyphene Propranolol Protriptyline Prulifloxacin Pyrilamine Quetiapine Quinacrine Quinestrol Ranitidine Remifentanil Rifampin Rimexolone Risperidone Ritonavir Rivastigmine Rizatriptan Rolapitant Rufloxacin Safinamide Scopolamine Sertraline Sevoflurane Sibutramine Solifenacin Sparfloxacin Sparsentan Stanozolol St John's Wort Sufentanil Sulbenicillin Sultamicillin Sumatriptan Tacrine Tapentadol Temocillin Terfenadine Testosterone Theophylline Thiethylperazine Thiopropazate Thioproperazine Thioridazine Thiotepa Thiothixene Thonzylamine Tianeptine Tibolone Ticarcillin Ticlopidine Tilidine Timiperone Timolol Tocilizumab Tolterodine Tramadol Trazodone Trifluoperazine Triflupromazine Trimeprazine Trimipramine Tripelennamine Triprolidine Tropicamide Trospium Tryptophan Umeclidinium Valbenazine Valethamate Varenicline Venlafaxine Vilazodone Vortioxetine Zidovudine Ziprasidone Zuclopenthixol Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Abiraterone Acetate Aripiprazole Lauroxil Digoxin Haloperidol Isavuconazonium Sulfate Lofexidine Metoprolol Nirmatrelvir Quinidine St John's Wort Terbinafine Tipranavir

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