Ispaghula
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Ispaghula consists of dried ripe seeds of Plantago Ovata, Ispaghula is a purgative. Ispaghula adsorbs water and increases the faecal bulk and promotes bowel movement.
Indications
Ispaghula is primarily indicated in conditions like Constipation, Irritable bowel syndrome, Strenuous defecation, and can also be given in adjunctive therapy as an alternative drug of choice in Chronic renal failure, Hypercholesterolemia.
Contraindications
Ispaghula is contraindicated in conditions like Intestinal obstruction.
Side Effects
The severe or irreversible adverse effects of Ispaghula, which give rise to further complications include Renal pigmentation. Ispaghula produces potentially life-threatening effects which include Anaphylactic shock, Bronchospasm, Rhinitis. which are responsible for the discontinuation of Ispaghula therapy. The signs and symptoms that are produced after the acute overdosage of Ispaghula include Abdominal pain, Intestinal obstruction, Abdominal distension, Flatulence.The symptomatic adverse reactions produced by Ispaghula are more or less tolerable and if they become severe, they can be treated symptomatically, these include Flatulence, Abdominal pain.
Warnings
Bulk laxative (ispaghula) should not be given to patients with pre-existing fecal impaction, intestinal obstruction or colonic atony. They should be taken with sufficient fluid and should not be taken immediately before going to bed. They should be avoided to patients who have difficult swallowing. It should be used with caution (if contains tartrazine) in patients with aspirin hypersensitivity, because may cause allergic reactions (including bronchial asthma). Discontinue use if skin eruption occurs.
High Risk Groups
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
3000 to 5000 mg (4000 (4000)) 12 hourly PO — For 2-3 Days
Child Dosage
300 mg/kg (300 (300)) 12 hourly Oral — As Required
Neonatal Dosage
( ) — Not recommended in this age group
Drug Interactions
No data regarding the interactions of Ispaghula was found.
Storage
Powder Store Below 40°C. Protect from Sunlight and Moisture.
Available Brands in Pakistan
No brands are recorded for this generic.