Lacidipine
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Lacidipine is a calcium-channel blocking agent, actions, uses and adverse effects similar to those of nifedipine. Lacidipine is used for the management of hypertension.
Indications
Lacidipine is primarily indicated in conditions like Hypertension.
Contraindications
Lacidipine is contraindicated in conditions like Hypersensitivity, Aortic stenosis, Left ventricular dysfunction.
Side Effects
The severe or irreversible adverse effects of Lacidipine, which give rise to further complications include Hypotension, Exacerbated angina, Gingival hypertrophy. The signs and symptoms that are produced after the acute overdosage of Lacidipine include Tachycardia, Prolonged peripheral vasodilation. The symptomatic adverse reactions produced by Lacidipine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Dyspnea, Palpitation, Flushing, Polyuria, Muscle cramps, Paresthesias, Ankle edema, Hypotensive crisis, Sexual impotence, Cold legs.
Warnings
Lacidipine should be used with caution in patients with kidney or liver disease. Consider decrease in dose of calcium channel blockers and monitor drug response in cirrhosis patients. It should be used with caution in the patient with hypotension. It should not be used in the cardiogenic shocks, recent Myocardial Infarction and in acute unstable angina. Sudden withdrawal of Lacidipine might be associated with an exacerbation of angina. The drug should be discontinued in the patient who experience ischemic pain following its administration.
High Risk Groups
Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
2 mg (2 (2)) 24 hourly PO — May be given upto 4-6 mg/day if needed
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Lacidipine is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAtenololEnhanced hypotensive effects when beta-blockers (e.g Atenolol) given with calcium-channel blockers (e.g Lacidipine).Cimetidine (HCl)DigoxinPropranolol (HCl) These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Storage
Store Below 30°C. Protect from Sunlight.
Available Brands in Pakistan
No brands are recorded for this generic.