Levamisole
Generic medicine reference
Overview
Levamisole is used with another cancer medicine (fluorouracil) to help make it work better against cancer of the colon.
Levamisole is available only with your doctor's prescription.
Indications
Levamisole is used with another cancer medicine (fluorouracil) to help make it work better against cancer of the colon.
Levamisole is available only with your doctor's prescription.
Contraindications
Levamisole is contraindicated in conditions like Hepatic disease, Hypersensitivity, Psoriatic arthropathy, Blood disorders.
Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Less common
Fever or chills unusual feeling of discomfort or weakness
Rare
Black, tarry stools blood in urine or stools cough or hoarseness lower back or side pain painful or difficult urination pinpoint red spots on skin unusual bleeding or bruising
Check with your doctor as soon as possible if any of the following side effects occur:
Less common
Sores in mouth and on lips
Rare
Blurred vision confusion convulsions (seizures) lip smacking or puffing numbness, tingling, or pain in face, hands, or feet paranoia (feelings of persecution) puffing of cheeks rapid or worm-like movements of tongue trembling or shaking trouble in walking uncontrolled movements of arms and legs
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Diarrhea metallic taste nausea
Less common
Anxiety or nervousness dizziness headache mental depression nightmares pain in joints or muscles skin rash or itching trouble in sleeping unusual tiredness or sleepiness vomiting
Levamisole may cause a temporary loss of hair in some people. After treatment has ended, normal hair growth should return.
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Warnings
Avoid use of alcohol and alcohol containing products while taking levamisole. Severe stomach upset, flushing and headache can occur. It is not recommended for use in pregnant or nursing women or in children. Avoid contact with people having cold, flu etc. as its use may decrease immunity. Avoid contact with those who had recently been vaccinated with a live vaccine. Alcohol should be avoided. It should be avoided in patients with preexisting blood disorder.
High Risk Groups
Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, and patients suffering from Liver Malfunction. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
120 to 150 mg (140 (135)) As recommended. PO — As a single dose.
Child Dosage
3 mg/kg (3 (3)) As recommended. Oral — Single Dose
Neonatal Dosage
3 mg/kg (3 (3)) As recommended. Oral — Single Dose
Drug Interactions
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Capecitabine Doxifluridine Fluorouracil Tegafur Warfarin
Storage
Tab, Susp Store Below 40°C.
Available Brands in Pakistan
7 active brands listed alphabetically.
ANTI WORM
ActiveALBRO PHARMA
DML: ANTI WORM
Tabs
BIO-BESOL
ActiveBIO LABS (PVT) LTD.
DML: BIO-BESOL
Syrup
KETRESS
ActiveICI PAKISTAN LTD.
DML: KETRESS
SyrupTabs
LEVAM
ActiveAMSON VACCINES & PHARMA (PVT) LTD.
DML: LEVAM
Tabs
NOCARIS
ActiveTHE SCHAZOO LABORATORIES LTD.
DML: NOCARIS
SyrupTabs
NOCARIS ADULT TAB
ActiveTHE SCHAZOO LABORATORIES LTD.
DML: NOCARIS ADULT TAB
Tabs
NOCARIS CHILDREN TAB
ActiveTHE SCHAZOO LABORATORIES LTD.
DML: NOCARIS CHILDREN TAB
Tabs
For educational purposes only. Check current guidelines and consult a qualified healthcare professional before making clinical decisions.
