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Lisinopril is used alone or in combination with other medications to treat high blood pressure in adults and children 6 years of age and older.
Lisinopril is also used in adults to treat congestive heart failure and to improve survival after a heart attack .
Lisinopril belongs to a class of medications called angiotensin-converting enzyme (ACE) inhibitors. It works by decreasing certain chemicals that tighten the blood vessels, so blood flows more smoothly and the heart can pump blood more efficiently.
High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys, and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.
Indications
Lisinopril is used alone or in combination with other medications to treat high blood pressure in adults and children 6 years of age and older.
Lisinopril is also used in adults to treat congestive heart failure and to improve survival after a heart attack .
Lisinopril belongs to a class of medications called angiotensin-converting enzyme (ACE) inhibitors. It works by decreasing certain chemicals that tighten the blood vessels, so blood flows more smoothly and the heart can pump blood more efficiently.
High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys, and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.
Contraindications
You should not use lisinopril if you are allergic to it or to any other ACE (angiotensin converting enzyme) inhibitor such as captopril , fosinopril , enalapril , benazepril , moexipril , perindopril , quinapril , ramipril , or trandolapril .
Do not take lisinopril within 36 hours before or after taking medicine that contains sacubitril (such as Entresto ).
If you have diabetes, do not take lisinopril with any medication that contains aliskiren (a blood pressure medicine).
Do not take lisinopril if you have a history of angioedema (severe allergic reaction).
To make sure this medicine is safe for you, tell your doctor if you have ever had:
heart disease , heart problems such as a recent heart attack; low blood pressure ; low white blood cell count; stomach pain; if you are on a low-salt diet; diabetes; liver disease ; or kidney disease (or if you are on dialysis).
You may also need to avoid taking lisinopril with aliskiren if you have kidney disease.
Stop using this medicine and tell your doctor right away if you become pregnant. Lisinopril can cause injury or death to the unborn baby if you use the medicine during your second or third trimester.
Do not breastfeed.
Side Effects
Get emergency medical help if you have signs of an allergic reaction to lisinopril: severe stomach pain, hives, difficult breathing, swelling of your face, lips, tongue, or throat.
Lisinopril may cause serious side effects. Call your doctor at once if you have:
a light-headed feeling, like you might pass out; high blood potassium - nausea , weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement; low white blood cell counts - fever , mouth sores, skin sores, sore throat , cough ; kidney problems - swelling, urinating less, feeling tired or short of breath; or liver problems - loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Common lisinopril side effects may include:
headache , dizziness; low blood pressure, cough; or chest pain.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
Do not use lisinopril if you are pregnant. It could harm the unborn baby. Stop using this medicine and tell your doctor right away if you become pregnant.
You should not use this medicine if you have ever had angioedema. Do not take lisinopril within 36 hours before or after taking medicine that contains sacubitril (such as Entresto).
If you have diabetes, do not use lisinopril together with any medication that contains aliskiren (such as Amturnide, Tekturna, Tekamlo).
You may also need to avoid taking lisinopril with aliskiren if you have kidney disease.
High Risk Groups
Do not use lisinopril if you are pregnant. It could harm the unborn baby. Stop using this medicine and tell your doctor right away if you become pregnant.
You should not use this medicine if you have ever had angioedema. Do not take lisinopril within 36 hours before or after taking medicine that contains sacubitril (such as Entresto).
If you have diabetes, do not use lisinopril together with any medication that contains aliskiren (such as Amturnide, Tekturna, Tekamlo).
You may also need to avoid taking lisinopril with aliskiren if you have kidney disease.
Adult Dosage
2.5 to 40 mg (21 (21.25)) 24 hourly PO —
Scraped Dose — Take lisinopril exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose..
You may take lisinopril with or without food.
Measure liquid medicine with the supplied measuring device (not a kitchen spoon).
Your blood pressure will need to be checked often and you may need frequent blood tests.
Tell your doctor if you have a planned surgery .
Call your doctor if you have ongoing vomiting or diarrhea , or if you are sweating more than usual. You can easily become dehydrated while taking lisinopril. This can lead to very low blood pressure, an electrolyte imbalance, or kidney failure .
If you have high blood pressure, keep using lisinopril even if you feel well. High blood pressure often has no symptoms.
Store tightly closed at room temperature, away from moisture and heat. Do not freeze.
Child Dosage
( ) — Not recommended in this age group
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Lisinopril can harm your kidneys, especially if you also use certain medicines for infections, cancer , or osteoporosis .
Tell your doctor about all your other medicines, especially:
a diuretic or "water pill" that may increase blood potassium such as spironolactone , triamterene , or amiloride ; NSAIDs (nonsteroidal anti-inflammatory drugs) - aspirin , ibuprofen ( Advil , Motrin ), naproxen ( Aleve ), celecoxib , diclofenac , indomethacin , meloxicam , and others; insulin or diabetes medications; medicine to prevent organ transplant rejection such as temsirolimus , sirolimus , or everolimus ; or heart or blood pressure medication.
This list is not complete. Other drugs may interact with lisinopril, including prescription and over-the-counter medicines, vitamins , and herbal products . Not all possible drug interactions are listed here.