Loperamide (HCl)

Loperamide (HCl) is antidiarrheal agent. Loperamide (HCl) is chemically related to haloperidol, acting directly on the intestinal wall o inhibit peristalsis. It acts more rapidly and is longer acting than diphenoxylate and codeine. Loperamide (HCl) is also effective to reduce the amount of discharge from ileostomies. Loperamide (HCl) is prepared by chemical synthesis. Loperamide (HCl) is administered orally.

Loperamide (HCl) is primarily indicated in conditions like Acute diarrhea, Chronic diarrhea in adults, Control of agitated states in elderly without confusion, Diarrhea, The pain of bowel colic in palliative care.

Loperamide (HCl) is contraindicated in conditions like Acute dysentery, Pseudomembranous colitis, Bloody diarrhea, High fever, Infectious diarrhea, Pseudomembranous colitis.

The signs and symptoms that are produced after the acute overdosage of Loperamide (HCl) include Constipation, Somnolence, Bradypnea, Muscular hypertonia, Neurological symptoms, Ileus. The symptomatic adverse reactions produced by Loperamide (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Drowsiness, Fatigue, Nausea, Vomiting, Skin reactions, Abdominal cramps, Urticaria, Dry mouth, Bullous eruptions, Pancreatitis.

Allergy alert: Do not use if you have ever had a rash or other allergic reaction to loperamide HCl Heart alert: Taking more than directed can cause serious heart problems or death Do not use if you have bloody or black stool in children under 12 years of age Ask a doctor before use if you have fever mucus in the stool a history of liver disease a history of abnormal heart rhythm Ask a doctor or pharmacist before use if you are taking a prescription drug. Loperamide may interact with certain prescription drugs. When using this product tiredness, drowsiness, or dizziness may occur. Be careful when driving or operating machinery. Stop use and ask a doctor if symptoms get worse diarrhea lasts for more than 2 days you get abdominal swelling or bulging. These may be signs of a serious condition. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.

Allergy alert: Do not use if you have ever had a rash or other allergic reaction to loperamide HCl Heart alert: Taking more than directed can cause serious heart problems or death Do not use if you have bloody or black stool in children under 12 years of age Ask a doctor before use if you have fever mucus in the stool a history of liver disease a history of abnormal heart rhythm Ask a doctor or pharmacist before use if you are taking a prescription drug. Loperamide may interact with certain prescription drugs. When using this product tiredness, drowsiness, or dizziness may occur. Be careful when driving or operating machinery. Stop use and ask a doctor if symptoms get worse diarrhea lasts for more than 2 days you get abdominal swelling or bulging. These may be signs of a serious condition. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.

4 to 16 mg (10 (10)) 24 hourly PO — Followed by 2mg/dose after each stool upto max dose of 16mg/day. Scraped Dose — drink plenty of clear fluids to help prevent dehydration caused by diarrhea not for use in children under 12 years of age adults and children 12 years and over: 2 softgels after the first loose stool; 1 softgel after each subsequent loose stool; but no more than 4 softgels in 24 hours

0.05 mg/kg (0.05 (0.05)) 6 hourly Oral — -

No neonatal dosage information is recorded for this medicine yet.

Loperamide (HCl) is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementCholestyramineColestipol (HCl)Desmopressin (Acetate)Plasma concentration of oral Desmopressin increased by Loperamide.Loperamide increase fastrointestinal absorption of desmopressin. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

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