Lopinovir
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Lopinovir is a protease inhibitor with antiviral activity against HIV.
Indications
Lopinovir is primarily indicated in conditions like Rocky mountain spotted fever, Trachoma, Urinary tract infection.
Contraindications
Lopinovir is contraindicated in conditions like Hypersensitivity.
Side Effects
The signs and symptoms that are produced after the acute overdosage of Lopinovir include Pancreatitis.The symptomatic adverse reactions produced by Lopinovir are more or less tolerable and if they become severe, they can be treated symptomatically, these include Hypercholesterolemia.
Warnings
No warnings information is recorded for this medicine yet.
High Risk Groups
Drug should not be given to Paediatrics, Pregnant Mothers, and patients suffering from Liver Malfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
400 mg (400 (400)) As recommended. oral —
Child Dosage
( ) —
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Lopinovir is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAbacavirRosuvastatinLopinovir significantly increased rosuvastatin exposure. Iin patients taking a combination of lopinavir, the dose of Rosuvastatin should be limited to 10 mg once daily. Tenofovir DisoproxilLopinavir has been shown to increase tenofovir concentrations.VORICONAZOLELopinavir may reduce serum concentration and efficacy of voriconazole. This combination should be avoided Vortioxetineincreases the level of vortioxetineuse alternative or decrease dose of vortioxetine by 50% These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Storage
No storage information is recorded for this medicine yet.
Available Brands in Pakistan
No brands are recorded for this generic.