Loprazolam
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Loprazolam is an intermediate-acting benzodiazepine with actions and general properties similar to those of diazepam. Loprazolam is used as a hypnotic in the short-term management of insomnia.
Indications
Loprazolam is primarily indicated in conditions like Insomnia, Nausea, vertigo, labyrinthine disorders.
Contraindications
Loprazolam is contraindicated in conditions like Myasthenia gravis, Respiratory depression, Acute pulmonary insufficiency, Sleep apnea syndrome.
Side Effects
The symptomatic adverse reactions produced by Loprazolam are more or less tolerable and if they become severe, they can be treated symptomatically, these include Vertigo, Drowsiness, Ataxia, Skin reactions, Light-headedness, Confusion, Dysuria, Muscle weakness, Tremor, Dysarthria, GI disturbance, Amnesia, Dependence, Salivation changes.
Warnings
Loprazolam should be used with caution in patients with respiratory disease, muscle weakness, history of drug or alcohol abuse, marked personality disorder; avoid regular use during pregnancy (risk of neonatal withdrawal symptoms); use only if clear indication such as seizure control (high doses during late pregnancy or labor may cause neonatal hypothermia, hypotonia and respiratory depression); breast-feeding (present in milk, avoid if possible); reduce dose in elderly and debilitated, and in hepatic (avoid if severe) and renal impairment (start with small doses if severe); avoid prolong use (abrupt withdrawal thereafter); porphyria. It should not be used alone to treat depression (or anxiety associated with depression) or psychosis
High Risk Groups
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
1 mg (1 (1)) 24 hourly PO — Dose can be increased to 2 mg if necessary.
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
No data regarding the interactions of Loprazolam was found.
Storage
No storage information is recorded for this medicine yet.
Available Brands in Pakistan
No brands are recorded for this generic.