Medicines/Generics/Lumefantrine

Lumefantrine

Generic medicine reference

Not yet clinically reviewed

This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.

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Overview

Lumefantrine (or benflumetol) is an antimalarial drug. It is only used in combination with artemether. The term "co-artemether" is sometimes used to describe this combination. Lumefantrine used in the treatment of malaria.

Indications

Lumefantrine is primarily indicated in conditions like Malaria caused by plasmodium falciparum.

Contraindications

Lumefantrine is contraindicated in conditions like Renal failure, Pulmonary edema.

Side Effects

The severe or irreversible adverse effects of Lumefantrine, which give rise to further complications include Fever, Chills. The symptomatic adverse reactions produced by Lumefantrine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Weakness, Dizziness, Headache, Fatigue, Nausea, Vomiting, Diarrhea, Myalgia, Palpitation, Sleep disturbance, Cough, Pleuritis, GI disturbance, Muscle pain, Stiffness, Loss of appetite, Rash.

Warnings

Should be use with caution in severely decreased kidney function, Severely decreased liver function, Heart disease. Birth control pills may not work properly while you are taking this medicine. Talk to your doctor about using an extra method of birth control.

High Risk Groups

Drug should not be given to Pediatrics, Pregnant Mothers, Cardiac / Hypertensive Patients, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Adult Dosage

240 mg (240 (240)) 12 hourly PO — Initially for once

Child Dosage

120 mg (120 (120)) As recommended. Initial dose, Repeated after 8,24,36,48 and 60 hours. 5-14 kg of children. — 16 mg/kg (16 (16)) As recommended. Oral — Initial dose , repeat after 8 hrs , 24 hrs and 48 hrs of 1st dose 240 mg (240 (240)) As recommended. Over 15 to 24 kg child — 360 mg (360 (360)) As recommended. Over 25 to 34 kg —

Neonatal Dosage

15 mg/kg (15 (15)) As recommended. Oral — Initial dose, repeat after 8 hrs. ,24 hrs. and 48 hrs of 1st dose

Drug Interactions

Lumefantrine is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementVORICONAZOLEadditive QTc-prolongation may occur. Concomitant therapy should be avoided. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Storage

Tab Store Below 30°C.

Available Brands in Pakistan

139 active brands listed alphabetically.

Lumefantrine

Available Brands in Pakistan

A-FANTRINE BD

AKILUM

AKILUM PLUS

ALAR

ALAR PLUS

ALTAMAL

ALUMAX

AMALAR

AMBLUM

AMBLUM FORT DS

AMBLUM FORTE

A-METHER

ANTIMAL TABLET

ANTMAL

ARCEVA

ARLUFA

ARMER

ARMIZOL

ARTEBLAX

ARTEBLAX L

ARTECAP

ARTECID

ARTECXIN

ARTECXIN DISPERSIBLE

ARTECXIN FORTE DISPERSIBLE

ARTEDAN CAPSULE

ARTEDAN TABLET

ARTELUM

ARTELUM EZ

ARTELUM FORTE

ARTEMAX

ARTEMAX PLUS

ARTEMEF

ARTEMET L

ARTEMEX L

ARTEMEX L FORTE

ARTEM PLUS DS

ARTEPEARL

ARTEPEARL DS

ARTHEGET EZ

ARTHEGET JUNIOR

ARTHER

ARTHER FORTE

ARTI

ARTI-L

ARTI-M

ARTIMINUM

ARTIMINUM FORT

ARTINE

ARTRINE

ATM DISPERSIBLE

BIANTIMAL

BIO LUMEFAR

CARAMETHER PLUS

CO-ART

CO-ARTENTIN DD

CO-MALEDOX

CO-MALEDOX QS

CO METHER

CO MISOMAL

CO-MISOMAL QS

DANKE FORT SUSPENSION

DANKE PLUS

DV-THER

DV-THER FORTE

ENTUM

FALCIGO

FALCIGO FORTE

FALCIM

FALCINIL

FALCINIL QS

FALCITHER DS

FALCITHER FORTE

FALCITHER PLUS

FALCITRIN OD

FALCITRIN PLUS

FANART

FANART