Lymecycline
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Lymecycline is a tetracycline broad-spectrum antibiotic. It is approximately 5,000 times more soluble than tetracycline base and is unique amongst tetracyclines in that it is absorbed by an active transport process across the intestinal wall. Bacteriostatic antibiotic with actions, adverse effects, and interactions almost similar to tetracycline.
Indications
Lymecycline is primarily indicated in conditions like Acne vulgaris, Amoebiasis, Bacterial infections, Brucellosis, Endocarditis, Ornithosis, Pneumonia, Psittacosis, Rickettsia, Syphilis, and can also be given in adjunctive therapy as an alternative drug of choice in Acute sinusitis, Chronic bronchitis, Helicobacter pylori infection, Soft tissue infections, Trachoma.
Contraindications
Lymecycline is contraindicated in conditions like Systemic lupus erythematosus.
Side Effects
The severe or irreversible adverse effects of Lymecycline, which give rise to further complications include Increased blood urea nitrogen, Hyperphosphatemia, Acidosis, Azotemia. Lymecycline produces potentially life-threatening effects which include Anaphylaxis, Acute hepatic dysfunction. which are responsible for the discontinuation of Lymecycline therapy. The symptomatic adverse reactions produced by Lymecycline are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Nausea, Diarrhea, Stomatitis, Vaginitis, Photosensitivity, Glossitis, Increased intracranial pressure, Enamel hypoplasia, Stomach pain.
Warnings
Tetracyclines should only be used with caution in patients with hepatic dysfunction, lest accumulation occurs with increased toxicity. Careful monitoring of dosage by serum levels is necessary. High dosage of tetracyclines may be hepatotoxic and great care should be used with concurrent administration of other hepatotoxic drugs. Tetracyclines should only be administered with great caution in patients with renal insufficiency lest accumulation occurs with increased toxicity. Dosage may require reduction. High dosage of tetracyclines may be nephrotoxic.
High Risk Groups
Drug should not be given to Pediatrics, Pregnant Mothers, patients suffering from Kidney dysfunction, and Neonates. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
1.428 to 2.857 mg/kg (2.1 (2.1425)) 8 hourly PO — -
2.857 to 4.285 mg/kg (3.6 (3.571)) As recommended. IV — As Required
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
No data regarding the interactions of Lymecycline was found.
Storage
Caps Store Below 25°C. Protect from Sunlight.
Available Brands in Pakistan
No active brands are currently recorded for this generic.
3 records are present but flagged "Unverified / Legacy" and excluded.
