Magnesium Trisilicate
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Magnesium Trisilicate is a non-systemic antacid used in the treatment of peptic ulceration. Neutralization of acid is slow in onset but relatively prolonged due to adsorbent properties of silicic acid formed in the stomach. It has a laxative effect in larger doses. Danger of magnesium toxicity in patients with renal failure.
Indications
Magnesium Trisilicate is primarily indicated in conditions like Dyspepsia, Heart burn, Hyperacidity.
Contraindications
Magnesium Trisilicate is contraindicated in conditions like Osteomalacia, Hypophosphatemia, Kidney disease.
Side Effects
The severe or irreversible adverse effects of Magnesium Trisilicate, which give rise to further complications include Hypermanganesemia, Kidney stones. The symptomatic adverse reactions produced by Magnesium Trisilicate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Diarrhea, Constipation, Nausea and vomiting.
Warnings
Do not exceed prescribed dose because it will cause diarrhea. Magnesium trisilicate should be use with caution in patients with renal impairment, stomach disorders and allergies
High Risk Groups
Drug should not be given to patients suffering from Kidney dysfunction. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
10 ml (10 (10)) 6 hourly PO —
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Magnesium Trisilicate is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementFamotidineBioavailability of Famotidine is decreased when administered with antacids (e.g Magnesium Trisilicate)Hydroxyquinolone SulphateIron Hydroxide Poly Maltose ComplexAntacids and mineral supplements containing Ca and Mg ( antacid like Magnesium Trisilicate) leads to impaired absorption of Iron These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Storage
Tab, Caps Store Below 40°C. Protect from Sunlight and Moisture.
Available Brands in Pakistan
No active brands are currently recorded for this generic.
1 record is present but flagged "Unverified / Legacy" and excluded.