Manganese
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Manganese is a trace element sometimes added to nutritional preparations for supposed increase in the haematinic effects of iron.
Indications
Manganese is primarily indicated in conditions like Rapid reversion to sinus rhythm.
Contraindications
Manganese is contraindicated in conditions like Liver cirrhosis.
Side Effects
The severe or irreversible adverse effects of Manganese, which give rise to further complications include Cholestatic jaundice, Extrapyramidal symptoms, Hypermanganesemia, Impaired biliary secretion. The signs and symptoms that are produced after the acute overdosage of Manganese include Dementia.
Warnings
Disease-related concerns:
• Biliary tract impairment: Use with caution in patients with biliary tract impairment; dose may need to be decreased or withheld.
• Hepatic impairment: Use with caution in patients with hepatic impairment; dose may need to be decreased or withheld.
Dosage form specific issues:
• Aluminum: The parenteral product may contain aluminum; toxic aluminum concentrations may be seen with high doses, prolonged use, or renal dysfunction. Premature neonates are at higher risk due to immature renal function and aluminum intake from other parenteral sources. Parenteral aluminum exposure of >4 to 5 mcg/kg/day is associated with CNS and bone toxicity; tissue loading may occur at lower doses (Federal Register, 2002). See manufacturer's labeling.
Other warnings/precautions:
• Appropriate use: Due to its highly acidic pH (pH 2.0), direct IV or IM injection is contraindicated; may result in severe tissue damage.
High Risk Groups
Disease-related concerns:
• Biliary tract impairment: Use with caution in patients with biliary tract impairment; dose may need to be decreased or withheld.
• Hepatic impairment: Use with caution in patients with hepatic impairment; dose may need to be decreased or withheld.
Dosage form specific issues:
• Aluminum: The parenteral product may contain aluminum; toxic aluminum concentrations may be seen with high doses, prolonged use, or renal dysfunction. Premature neonates are at higher risk due to immature renal function and aluminum intake from other parenteral sources. Parenteral aluminum exposure of >4 to 5 mcg/kg/day is associated with CNS and bone toxicity; tissue loading may occur at lower doses (Federal Register, 2002). See manufacturer's labeling.
Other warnings/precautions:
• Appropriate use: Due to its highly acidic pH (pH 2.0), direct IV or IM injection is contraindicated; may result in severe tissue damage.
Adult Dosage
200 mcg (200 (200)) As recommended. PO — As required.
Scraped Dose — Excipient information presented when available (limited, particularly for generics); consult specific product labeling. [DSC] = Discontinued product
Capsule, Oral, as chelated:
MN-50: Elemental manganese 16.67 mg
Solution, Intravenous, as chloride:
Generic: Elemental manganese 0.1 mg/mL (10 mL)
Solution, Intravenous, as sulfate [preservative free]:
Generic: Elemental manganese 0.1 mg/mL (10 mL [DSC])
Tablet, Oral, as aspartate:
Generic: 93 mg [elemental manganese 25 mg]
Tablet, Oral, as chelated:
Mangimin: Elemental manganese 10 mg [corn free, rye free, wheat free]
Generic: Elemental manganese 15 mg [DSC], Elemental manganese 50 mg
Tablet, Oral, as gluconate:
Generic: 50 mg [elemental manganese 5.7 mg]
Child Dosage
15 ug (15 (15)) As recommended. —
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
There are no known significant interactions.
Storage
No storage information is recorded for this medicine yet.
Available Brands in Pakistan
No brands are recorded for this generic.