Question 1

What is Mannitol used for?

Accepted Answer

Mannitol is a diuretic that is used to reduce swelling and pressure inside the eye or around the brain.

Mannitol is also used to help your body produce more urine.  mannitol injection is used in people with kidney failure , to remove excess water and toxins from the body.

Mannitol is sometimes given so that your body will produce enough urine to be collected and tested. This helps your doctor determine if your kidneys are working properly.

Mannitol may also be used for purposes not listed in this medication guide.

Question 2

What is the adult dose of Mannitol?

Accepted Answer

0.2 g/ kg/dose (0.2 (0.2)) As recommended. IV Inf — Test Dose, Max. 12.5gm over 3-5 min, If there is no diuresis within 2 hrs. discontinue mannitol
0.25 to 0.5 g/ kg/dose (0.38 (0.375)) 6 hourly IV Inf — Maintenance dose
0.5 to 1 g/ kg/dose (0.75 (0.75)) As recommended. IV Inf — Initial dose
10 to 20 % (15 (15)) 24 hourly IV Inf —

Question 3

What is the paediatric dose of Mannitol?

Accepted Answer

0.25 to 0 g/ug (0.12 (0.125)) As recommended.   —  
16.66 to 66.66 mg/kg.min (42 (41.66)) As recommended. IV Infusion — Once for 30 Minutes .Can be repeated

Question 4

What are the side effects of Mannitol?

Accepted Answer

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers right away if you have:

swelling in your hands or lower legs, rapid weight gain; little or no urination; shortness of breath (even while lying down); wheezing , gasping for breath, cough with foamy mucus; chest pain, fast heartbeats; headache , or feeling like you might pass out; a seizure; painful or difficult urination; pain, bruising, irritation, or skin changes where the injection was given; dehydration symptoms --feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin; or signs of an electrolyte imbalance --increased thirst or urination, confusion, vomiting, constipation , muscle pain or weakness, leg cramps, bone pain, lack of energy, irregular heartbeats, tingly feeling.

Common side effects of mannitol injection may include:

increased urination; nausea, vomiting; fever, chills, headache, runny nose; chest pain; rash; or dizziness, blurred vision.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Question 5

Who should not take Mannitol?

Accepted Answer

You should not receive mannitol if you are allergic to it, or if you have:

severe or long-term kidney disease; swelling or congestion in your lungs; severe heart failure; bleeding in your brain that is not related to surgery; severe dehydration; or if your kidneys have already shut down and you are unable to urinate.

Tell your doctor if you have ever had:

kidney disease; heart disease ; or an electrolyte imbalance (such as low levels of potassium or sodium in your blood).

Tell your doctor if you are pregnant or breastfeeding.

Question 6

What does Mannitol interact with?

Accepted Answer

Mannitol can harm your kidneys, especially if you also use certain medicines for infections, cancer, osteoporosis , organ transplant rejection, bowel disorders, high blood pressure , or pain or arthritis (including Advil, Motrin, and Aleve).

Tell your doctor about all your other medicines, especially a diuretic or "water pill."

Other drugs may affect mannitol, including prescription and over-the-counter medicines, vitamins , and herbal products . Tell your doctor about all your current medicines and any medicine you start or stop using.

Mannitol

Available Brands in Pakistan

MACTOL

MACTOL 20%

MANNILYTE

MANNITOL

MANNITOL

MANNITOL

MANNITOL 20%

MANNITOZAF

MARITOL

MEDISOL MANNITOL

UNIRETIC