Mazindol
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Mazindol is a sympathomimetic amine, which is similar to an amphetamine. It is also known as an anorectic or an anorexigenic drug.It stimulates the central nervous system (nerves and brain), which increases your heart rate and blood pressure and decreases your appetite. Sympathomimetic appetite suppressants are used in the short-term treatment of obesity. Their appetite-reducing effect tends to decrease after a few weeks. Because of this, these medicines are useful only during the first few weeks of a weight-loss program mazindol is thought to inhibit the reuptake of norepinephrine rather than to cause its release.
Indications
Mazindol is primarily indicated in conditions like Obesity, and can also be given in adjunctive therapy as an alternative drug of choice in Narcolepsy.
Contraindications
Mazindol is contraindicated in conditions like Epilepsy,Hypertension,Hyperthyroidism,Cardiovascular disease,Arteriosclerosis.
Side Effects
The severe or irreversible adverse effects of Mazindol, which give rise to further complications include Allergic reactions, Restlessness, High blood pressure, Nervousness.Mazindol produces potentially life-threatening effects which include ciculatory collapse. which are responsible for the discontinuation of Mazindol therapy.The signs and symptoms that are produced after the acute overdosage of Mazindol include Seizures, Hyperthermia, Hallucinations, Tremor, Agressive behavior, Arrhythmias.The symptomatic adverse reactions produced by Mazindol are more or less tolerable and if they become severe, they can be treated symptomatically, these include Irritability, Vomiting, Diarrhea, Insomnia, Swelling of face.
Warnings
Use caution while driving and operating machinery as it causes dizziness and tiredness. It is a habit forming drug so withdrawal effects occurs. It should be withdraw gradually.
High Risk Groups
Drug should not be given to Paediatrics, Pregnant Mothers, and Cardiac / Hypertensive Patients.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
1 to 2 mg (1.5 (1.5)) 8 hourly Oral — Mazindol should be taken before meal.
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
No data regarding the interactions of Mazindol was found.
Storage
Store in a well closed container, Below 30°C.
Available Brands in Pakistan
No brands are recorded for this generic.