Medicines/Generics/Mebeverine

Mebeverine

Generic medicine reference

Not yet clinically reviewed

This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.

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Overview

Mebeverine (HCl) is antispasmodic agent with direct action on the smooth muscle of the gastrointestinal tract. It relieves the abdominal pain and cramps. It is a second generation papaverine analog. It was first registered in 1965. Mebeverine (HCl) is administered orally.

Indications

Mebeverine is primarily indicated in conditions like Adjunct in GI-disorders, Chronic irritable colon, Gastrointestinal spasm, Irritable bowel syndrome, Mucous colitis, Spastic colon, Spastic constipation.

Contraindications

Mebeverine

Side Effects

The symptomatic adverse reactions produced by Mebeverine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Anorexia, Insomnia, Allergic reactions, Erythematous rash, Angioedema, Gastrointestinal disturbances

Warnings

Pregnancy and breast-feeding, also avoid in porphyria. Should be used with care in marked hepatic or renal impairment & heart block.

High Risk Groups

Drug should not be given to Pediatrics, and Neonates. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Adult Dosage

135 to 150 mg (140 (142.5)) 8 hourly PO — 20 mins before meals,

Child Dosage

100 mg (100 (100)) As recommended. For 8-10 years — 25 mg (25 (25)) As recommended. For 3-4 years — 50 mg (50 (50)) As recommended. For 4-8 years —

Neonatal Dosage

No neonatal dosage information is recorded for this medicine yet.

Drug Interactions

No data regarding the interactions of Mebeverine was found.

Storage

Tab Store Below 40°C.