Medicines/Generics/Mecobalamin

Mecobalamin

Generic medicine reference

Not yet clinically reviewed

This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.

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Overview

Mecobalamin is a vitamin B-12 co-enzyme that occurs in blood and cerebrospinal fluid. Mecobalamin is taken by nerve tissues more actively and extensively than other homologues of vitamin B12. Mecobalamin accelerates the synthesis of nucleic acid in bone marrow as well as promotes the maturation and division of erythroblast and heme synthesis, resulting in an increase in erythrocyte (RBCs) production.

Indications

Mecobalamin is primarily indicated in conditions like Congenital cobalamin malabsorption, Congenital intrinsic factor deficiency, Homocystenemia, Methylmalonylacidurias, Peripheral neuropathy, Pernicious anemia, Post gastrectomy Vit-B-12 deficiency, Transcobalamin II deficiency, Vitamin B12 deficiency.

Contraindications

Mecobalamin is contraindicated in conditions like Hypersensitivity to any component of product.

Side Effects

Mecobalamin produces potentially life-threatening effects which include Cardiac arrhythmia, Aggravation of acidosis. which are responsible for the discontinuation of Mecobalamin therapy. The symptomatic adverse reactions produced by Mecobalamin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Nausea, Vomiting, Anorexia, Diarrhea, Tachycardia, Sweating, Skin Rash, Hot sensation, Allergic hypersensitivity reactions.

Warnings

Mecobalamin should be used with caution in patients with any pre-existing illnesses or any allergies. This medication should be used only as directed during pregnancy or lactation.

High Risk Groups

If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Adult Dosage

250 to 1000 mcg (620 (625)) As recommended. IM, IV — Alternate days for 1 to 2 weeks followed by 250 mcg weekly. Then for maintenance administer 1000 mcg every 2-3 weeks. 500 mcg (500 (500)) 8 hourly PO — Treatment depends upon extent of iron deficiency.

Child Dosage

No child dosage information is recorded for this medicine yet.

Neonatal Dosage

No neonatal dosage information is recorded for this medicine yet.

Drug Interactions

No data regarding the interactions of Mecobalamin was found.

Storage

Injection Store Between 15°C-30°C. Do not Freeze.

Available Brands in Pakistan

21 active brands listed alphabetically.

Mecobalamin

Available Brands in Pakistan

BEZEL

BIOCOBAL

COBOLMIN

G-COBAL

INCOBAL

LIZOBAL

MABIL

M-COBAL

MECOBAL

MEDICOBAL

METHYCOBAL

M-KAMIN

MYLAXON

NERVON

NEUROMET

NEW-12

QBAL

T-KOBAL

TONE-UP

VIO-COBAL

XYSTER