Medroxyprogesterone Acetate
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Medroxyprogesterone tablets are used to treat abnormal menstrual bleeding , absent or irregular menstrual periods (amenorrhea) and to prevent thickening of the lining of the uterus ( endometrial hyperplasia ) in postmenopausal women who are taking estrogen hormone replacement therapy. Medroxyprogesterone is a progestin hormone.
Indications
Medroxyprogesterone tablets are used to treat abnormal menstrual bleeding , absent or irregular menstrual periods (amenorrhea) and to prevent thickening of the lining of the uterus ( endometrial hyperplasia ) in postmenopausal women who are taking estrogen hormone replacement therapy. Medroxyprogesterone is a progestin hormone.
Contraindications
You should not use this medicine if you are allergic to medroxyprogesterone, or if you have:
abnormal vaginal bleeding that has not been checked by a doctor; liver disease; a history of heart attack , stroke, or blood clot; or a history of hormone-related cancer, or cancer of the breast, uterus/cervix, or vagina.
Medroxyprogesterone may cause birth defects. Do not use if you are pregnant. Tell your doctor right away if you become pregnant.
Medroxyprogesterone should not be used to prevent heart disease, stroke, or dementia. This medicine may actually increase your risk of developing these conditions.
To make sure medroxyprogesterone is safe for you, tell your doctor if you have:
heart problems; liver problems; asthma ; migraine headaches; a thyroid disorder; endometriosis (severe pelvic pain); jaundice caused by pregnancy or birth control pills ; kidney disease; high or low blood levels of calcium; a seizure; diabetes; or lupus .
Using this medicine can increase your risk of blood clots, stroke, or heart attack, especially if you have high blood pressure , diabetes, high cholesterol , if you are overweight , or if you smoke.
Long-term use of medroxyprogesterone may increase your risk of cancer of the breast, uterus, or ovaries. Talk with your doctor about this risk.
Do not breastfeed.
Side Effects
Get emergency medical help if you have signs of an allergic reaction to medroxyprogesterone : hives ; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using this medicine and call your doctor at once if you have:
signs of a stroke - sudden numbness or weakness (especially on one side of the body), sudden severe headache , slurred speech, problems with vision or balance; signs of a blood clot - sudden vision loss, stabbing chest pain, feeling short of breath, coughing up blood, pain or warmth in one or both legs; heart attack symptoms - chest pain or pressure, pain spreading to your jaw or shoulder, nausea , sweating; liver problems - loss of appetite, upper stomach pain, tiredness, fever, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); unusual vaginal bleeding; confusion, memory problems; a breast lump; or symptoms of depression - sleep problems, weakness, tired feeling, mood changes.
Common medroxyprogesterone side effects may include:
spotting or breakthrough bleeding ; changes in your menstrual periods; vaginal itching or discharge; headache, dizziness , feeling nervous or depressed; breast tenderness or discharge; stomach discomfort, bloating , nausea, vomiting ; itching, rash, acne , hair growth, hair loss ; premenstrual type symptoms (bloating, fluid retention , mood changes); weight gain; bruising or swelling of your veins; tiredness, trouble sleeping; or vision changes and difficulty wearing contact lenses.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
You should not use medroxyprogesterone if you are pregnant, or if you have liver disease, a hormone-related cancer such as breast or uterine cancer, a history of stroke or blood clot, or abnormal vaginal bleeding that has not been checked by a doctor.
Medroxyprogesterone should not be used to prevent heart disease, stroke, or dementia . This medicine may actually increase your risk of developing these conditions. Long-term use of medroxyprogesterone may increase your risk of breast cancer, heart attack, stroke, or blood clot. Talk with your doctor about your individual risk.
High Risk Groups
You should not use medroxyprogesterone if you are pregnant, or if you have liver disease, a hormone-related cancer such as breast or uterine cancer, a history of stroke or blood clot, or abnormal vaginal bleeding that has not been checked by a doctor.
Medroxyprogesterone should not be used to prevent heart disease, stroke, or dementia . This medicine may actually increase your risk of developing these conditions. Long-term use of medroxyprogesterone may increase your risk of breast cancer, heart attack, stroke, or blood clot. Talk with your doctor about your individual risk.
Adult Dosage
Scraped Dose — Take medroxyprogesterone exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.
Medroxyprogesterone is usually given for only a few days in a row each month.
Have regular physical exams and self-examine your breasts for lumps on a monthly basis while using this medicine.
If you need major surgery or will be on long-term bed rest, you may need to stop using medroxyprogesterone for a short time. This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using medroxyprogesterone.
Store at room temperature away from moisture and heat.
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Other drugs may interact with medroxyprogesterone, including prescription and over-the-counter medicines, vitamins , and herbal products . Tell your doctor about all other medicines you use.
Storage
No storage information is recorded for this medicine yet.
Available Brands in Pakistan
1 active brand listed alphabetically.
DIMPLE
ActiveAGP (PRIVATE) LTD.
DML: DIMPLE
Tabs
