Mefruside
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Mefruside is a benzene disulfonamide derivative related to the benzothiadiazine or thiazide diuretics. Mefruside is administered orally. Mefruside is used in the treatment of fluid overload and in control of high blood pressure.
Indications
Mefruside is primarily indicated in conditions like Edema, Hypertension.
Contraindications
Mefruside is contraindicated in conditions like Hypercalcemia, Addison's disease, Hypersensitivity.
Side Effects
The severe or irreversible adverse effects of Mefruside, which give rise to further complications include Hyperuricemia, Impaired glucose tolerance, Acute gout. Mefruside produces potentially life-threatening effects which include Hypokalemia. which are responsible for the discontinuation of Mefruside therapy.The signs and symptoms that are produced after the acute overdosage of Mefruside include Coma, Lethargy, CNS depression. The symptomatic adverse reactions produced by Mefruside are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dyspepsia, Increased intracranial pressure, Hypovolemia, Acute urinary retention.
Warnings
No warnings information is recorded for this medicine yet.
High Risk Groups
Drug should not be given to Paediatrics, Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
0.178 to 0.714 mg/kg (0.45 (0.446)) 24 hourly PO — -
Child Dosage
( ) — Not recommended in this age group
Neonatal Dosage
( ) — Not recommended in this age group
Drug Interactions
No data regarding the interactions of Mefruside was found.
Storage
No storage information is recorded for this medicine yet.
Available Brands in Pakistan
No brands are recorded for this generic.