Mepacrine (HCl)
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Mepacrine (HCl) is an antiprotozoal agent. Mepacrine (HCl) is an acridine derivative, widely used during the second world war as an antimalarial agent, but now Mepacrine (HCl) is no longer used for this purpose, rather more safer and newer drugs are preferred. Mepacrine (HCl) is mainly used for the treatment of giardiasis. It has also been used locally for the treatment of certain cutaneous leishmaniasis.
Indications
Mepacrine (HCl) is primarily indicated in conditions like Discoid lupus erythematosus, Giardiasis.
Contraindications
Mepacrine (HCl) is contraindicated in conditions like Psoriasis,Alcohol abuse,Hypersensitivity to the drug.
Side Effects
The symptomatic adverse reactions produced by Mepacrine (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Nausea and vomiting, GI disturbance, CNS stimulation, Transient acute toxic psychosis, Yellow discoloration of skin and urine,
Warnings
Mepacrine (HCl) should be used with caution in patients with hepatic impairment; elderly, history of psychosis. Avoid in psoriasis, Porphyria
High Risk Groups
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
100 mg (100 (100)) 8 hourly PO — Should be given for 5 to 7 days.
Child Dosage
2 mg/kg (2 (2)) As recommended. Maximum 300mg daily. —
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
No data regarding the interactions of Mepacrine (HCl) was found.
Storage
No storage information is recorded for this medicine yet.
Available Brands in Pakistan
No brands are recorded for this generic.