Medicines/Generics/Mesterolone

Mesterolone

Generic medicine reference

Not yet clinically reviewed

This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.

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Overview

Mesterolone is a sex hormone with actions and uses similar to Testosterone. Mesterolone is used to treat some menstrual disorders, in breast cancer and for suppression of lactation.

Indications

Mesterolone is primarily indicated in conditions like Androgen deficiency and male infertility, Disorders due to androgen deficiency, Hypogonadism, Infertility.

Contraindications

Mesterolone is contraindicated in conditions like Prostatic cancer, Hepatic carcinoma.

Side Effects

Mesterolone produces potentially life-threatening effects which include Liver tumors. which are responsible for the discontinuation of Mesterolone therapy. The symptomatic adverse reactions produced by Mesterolone are more or less tolerable and if they become severe, they can be treated symptomatically, these include Erectile disturbance, Frequent & persistent erection, Hepatic tumors.

Warnings

Mesterolone should be used with caution in patients with any disease, especially cancer of the prostate or breast, liver, heart, kidney disease, allergy, enlarged prostate. High dosage, long term use of androgens has been related to liver cancer. This drug should not be used during pregnancy or lactation. Females should be monitored for signs of virilization, such as deepening of the voice, facial hair, acne, menstrual irregularity or clitoral enlargement, consult the doctor promptly if any of these symptoms occurs. Use in children should not be recommended due to the possibility this drug may have undesirable effects related to the growth of the child. It should be used with extreme caution in geriatric (men) because they are at higher risk for developing enlarged prostates or prostate cancer when using this medication.

High Risk Groups

If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Adult Dosage

25 mg (25 (25)) 8 hourly PO — Initiation therapy for several months. 50 to 75 mg (62 (62.5)) As recommended. PO — Daily in divided doses.

Child Dosage

Not applicable in this age group ( ) —

Neonatal Dosage

Not applicable in this age group ( ) —

Drug Interactions

No data regarding the interactions of Mesterolone was found.

Storage

Tab Store Below 40°C. Protect from Moisture.