Mesterolone
Generic medicine reference
Overview
Mesterolone is a sex hormone with actions and uses similar to Testosterone. Mesterolone is used to treat some menstrual disorders, in breast cancer and for suppression of lactation.
Indications
Mesterolone is primarily indicated in conditions like Androgen deficiency and male infertility, Disorders due to androgen deficiency, Hypogonadism, Infertility.
Contraindications
Mesterolone is contraindicated in conditions like Prostatic cancer, Hepatic carcinoma.
Side Effects
Mesterolone produces potentially life-threatening effects which include Liver tumors. which are responsible for the discontinuation of Mesterolone therapy. The symptomatic adverse reactions produced by Mesterolone are more or less tolerable and if they become severe, they can be treated symptomatically, these include Erectile disturbance, Frequent & persistent erection, Hepatic tumors.
Warnings
Mesterolone should be used with caution in patients with any disease, especially cancer of the prostate or breast, liver, heart, kidney disease, allergy, enlarged prostate. High dosage, long term use of androgens has been related to liver cancer. This drug should not be used during pregnancy or lactation. Females should be monitored for signs of virilization, such as deepening of the voice, facial hair, acne, menstrual irregularity or clitoral enlargement, consult the doctor promptly if any of these symptoms occurs. Use in children should not be recommended due to the possibility this drug may have undesirable effects related to the growth of the child. It should be used with extreme caution in geriatric (men) because they are at higher risk for developing enlarged prostates or prostate cancer when using this medication.
High Risk Groups
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
25 mg (25 (25)) 8 hourly PO — Initiation therapy for several months.
50 to 75 mg (62 (62.5)) As recommended. PO — Daily in divided doses.
Child Dosage
Not applicable in this age group ( ) —
Neonatal Dosage
Not applicable in this age group ( ) —
Drug Interactions
No data regarding the interactions of Mesterolone was found.
Storage
Tab Store Below 40°C. Protect from Moisture.
Available Brands in Pakistan
2 active brands listed alphabetically.
PROVIRON
ActiveBAYER SCHERING PHARMA.
DML: PROVIRON
Tabs
STERELON
ActiveHANSEL PHARMACUEUTICAL PVT (LTD)
DML: STERELON
Tabs
For educational purposes only. Check current guidelines and consult a qualified healthcare professional before making clinical decisions.